283 640

Cited 0 times in

Is There Relationship between Brain Atrophy and Higher Incidence of Hip Fracture in Old Age? -A Preliminary Study-

Authors
 Tae Hoon Kim  ;  Seung Woo Suh  ;  Jin-Ho Hwang  ;  Tae Hwan Yoon 
Citation
 YONSEI MEDICAL JOURNAL, Vol.54(6) : 1511-1515, 2013 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2013
MeSH
Aged ; Aged, 80 and over ; Atrophy/pathology* ; Brain/pathology* ; Female ; Hip Fractures/pathology* ; Humans ; Incidence ; Magnetic Resonance Imaging ; Male
Keywords
Hip fracture ; brain atrophy ; relationship for high incidence of fall
Abstract
PURPOSE:
The studies on the correlation between incidence of fall and brain atrophy have been going on to find out the cause of fall and its prevention. The purpose of this study was to explore the relationship between incidence of hip fracture and brain volume, measured by magnetic resonance image.
MATERIALS AND METHODS:
A total of 14 subjects with similar conditions (age, height, weight, and past history) were selected for this study. Fracture group (FG) was consisted of 5 subjects with intertrochanteric fracture. Control group (CG) had 9 subjects without intertrochanteric fracture. MRI-based brain volumetry was done in FG and CG with imaging software. Total brain (tBV), absolute cerebellar volumes (aCV) and relative cerebellar volumes (rCV) were compared between two groups. Student t-test was used to statistically analyze the results.
RESULTS:
In FG, average tBV, aCV and rCV were 1034.676±38.80, 108.648±76.80 and 10.50±0.72 cm³, respectively. In CG, average tBV, aCV and rCV were found to be 1106.459±89.15, 114.899±98.06 and 10.39±0.53 cm³, respectively, having no statistically significant difference (p>0.05).
CONCLUSION:
There was no significant difference between the fracture and control groups. Patients with neurologic disease such as cerebellar ataxia definitely have high incidence of fall that causes fractures and have brain changes as well. However, FG without neurologic disease did not have brain volume change. We consider that high risk of fall with hip fracture might decrease brain function which is not obvious to pickup on MRI.
Files in This Item:
T201304001.pdf Download
DOI
10.3349/ymj.2013.54.6.1511
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Yoon, Tae Hwan(윤태환) ORCID logo https://orcid.org/0000-0002-2859-5240
Hwang, Jin Ho(황진호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88427
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links