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Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System

 Seulkee Park  ;  Jun Soo Jeong  ;  Jong Ju Jeong  ;  Sang-Wook Kang  ;  Jae Hyun Park  ;  Cho-Rok Lee  ;  Haeng Rang Ryu 
 Journal of Korean Medical Science, Vol.28(5) : 693-699, 2013 
Journal Title
 Journal of Korean Medical Science 
Issue Date
Thyroid carcinomas are uncommon in childhood and adolescence. The aim of this study was to analyze clinical features and clinical outcomes of thyroid cancer in the pediatric population treated in the Yonsei University Health System. From September 1982 to June 2009, 90 patients (75 females, 15 males; female:male ratio of 5:1) with differentiated thyroid carcinoma were identified in our institute. The mean age at diagnosis was 15.8 yr old (range 4.8-19.9 yr). Cervical masses were most common clinical manifestations at diagnosis in 65 patients (72.2%). Forty-two patients underwent less than total thyroidectomy and 18 patients underwent total thyroidectomy. Thirty patients (33.3%) had lateral neck lymph node metastasis and seven patients (7.8%) had lung metastasis at the time of surgery. Among the 90 patients, recurrence occurred in 14 patients (15.5%). Mean follow-up period for patients with differentiated thyroid carcinoma was 81.6 months (13-324 months). No patients died of differentiated thyroid carcinoma. Patients with differentiated thyroid carcinoma who were < 20-yr-of-age were present with aggressive local disease and a high frequency of lymph node and distant metastasis. It is recommended that pediatric thyroid cancer should be managed mostly using proper surgical approach with thyroidectomy and lymph node dissection when indicated.
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실)
Yonsei Authors
강상욱(Kang, Sang Wook) ; 남기현(Nam, Kee Hyun) ; 박정수(Park, Cheong Soo) ; 이초록(Lee, Cho Rok) ; 정웅윤(Chung, Woung Youn) ; 정종주(Jeong, Jong Ju)
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