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Staging laparoscopy for the management of early-stage ovarian cancer: a metaanalysis

Authors
 Hyun Jong Park  ;  Dong Wook Kim  ;  Ga Won Yim  ;  Eun Ji Nam  ;  Sunghoon Kim  ;  Young Tae Kim 
Citation
 AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol.209(58) : 1-8, 2013 
Journal Title
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
ISSN
 0002-9378 
Issue Date
2013
MeSH
Female ; Humans ; Laparoscopy/methods* ; Neoplasm Staging/methods* ; Ovarian Neoplasms/surgery* ; Ovary/surgery*
Keywords
Female ; Humans ; Laparoscopy/methods* ; Neoplasm Staging/methods* ; Ovarian Neoplasms/surgery* ; Ovary/surgery*
Abstract
OBJECTIVE: We sought to perform a quantitative analysis on operative outcomes of laparoscopic staging surgery in patients with presumed early-stage ovarian cancer using a metaanalysis.

STUDY DESIGN: Electronic searches for studies of laparoscopic staging surgery in patients with ovarian cancer were performed within 3 electronic databases (Medline, Embase, and the Cochrane Library) using the key words "ovarian cancer," "early stage," "laparoscopy," "staging surgery," "staging laparoscopy," and "recurrence." Two authors independently screened articles, and those meeting the defined inclusion/exclusion criteria were included in the metaanalysis.

RESULTS: We identified 11 observational studies. The combined results of 3 retrospective studies showed that the estimated blood loss in laparoscopy was significantly lower than that for laparotomy (P < .001). The overall upstaging rate after laparoscopic surgery was 22.6% (95% confidence interval [CI], 18.1-27.9%) without significant heterogeneity among all study results. The overall incidence of conversion from laparoscopy to laparotomy was 3.7% (95% CI, 2.0-6.9%). The overall rate of recurrence in studies with a median follow-up period of ≥19 months was 9.9% (95% CI, 6.7-14.4%).

CONCLUSION: Through our quantitative analysis, we concluded that the operative outcomes of a laparoscopic approach in patients with early-stage ovarian cancer could be compatible with those of laparotomy. In the future, further randomized controlled trials may be needed
Full Text
http://www.sciencedirect.com/science/article/pii/S0002937813003621
DOI
10.1016/j.ajog.2013.04.013
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Wook(김동욱) ORCID logo https://orcid.org/0000-0002-5025-1532
Kim, Sung Hoon(김성훈) ORCID logo https://orcid.org/0000-0002-1645-7473
Kim, Young Tae(김영태) ORCID logo https://orcid.org/0000-0002-7347-1052
Nam, Eun Ji(남은지) ORCID logo https://orcid.org/0000-0003-0189-3560
Park, Hyun Jong(박현종)
Yim, Ga Won(임가원)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/87941
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