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Successful Graft Recovery from Thrombotic Acute Kidney Injury i n a Kidney Transplant Patient with Antiphospholipid Syndrome

 Younjeong Choi  ;  Hyewon Lee  ;  Yujung Yun  ;  Youngki Lee  ;  Eudong Hwang  ;  Hyeonjoo Jeong  ;  Beom Seok Kim 
 Journal of the Korean Society for Transplantation (대한이식학회지), Vol.27(3) : 128-131, 2013 
Journal Title
Journal of the Korean Society for Transplantation(대한이식학회지)
Issue Date
Antiphospholipid syndrome nephropathy ; Antiphospholipid syndrome ; Antiphospholipid antibodies ; Lupus coagulation inhibitor ; Kidney transplantation
Antiphospholipid syndrome nephropathy (APSN) is well documented in the literature as the renal involvement of the antiphospholipid syndrome (APS). A review of literature also shows that among antiphospholipid antibodies, lupus anticoagulant (LA) positivity is recognized as the strongest risk factor for APSN. In addition, APSN is also known to be associated with a poor functional outcome in the first posttransplant year. Therefore, it is a general belief that renal transplantation may be life threatening in APS patients. Furthermore, the presence of LA at the time of transplantation is particularly associated with a high rate of allograft APSN and the consequent poor transplantation outcomes. Here, we report the case that thrombotic acute kidney injury due to APSN after kidney transplantation can be successfully treated if anticoagulation therapy is timely applied with a prompt diagnosis.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Beom Seok(김범석) ORCID logo https://orcid.org/0000-0002-5732-2583
Yun, Yu Jung(윤유정)
Lee, Young Ki(이영기)
Lee, Hye Won(이혜원) ORCID logo https://orcid.org/0000-0002-3552-3560
Jeong, Hyeon Joo(정현주) ORCID logo https://orcid.org/0000-0002-9695-1227
Choi, Youn Jeong(최연정)
Hwang, Eu Dong(황의동)
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