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낭성 섬유증이 없었던 환자에서 폐이식 후 발생한 Burkholderia cepacia 폐렴

Other Titles
 A Case of Burkholderia cepacia Pneumonia after Lung Transplantation in a Recipient without Cystic Fibrosis 
 조진선  ;  나성원  ;  박무석  ;  소 윤  ;  이 반  ;  고신옥  ;  백효채 
 Korean Journal of Critical Care Medicine, Vol.28(3) : 187-191, 2013 
Journal Title
Korean Journal of Critical Care Medicine
Issue Date
Burkholderia cepacia ; lung transplantation ; pneumonia
Burkholderia cepacia is a highly virulent pathogen known to cause opportunistic infections in immunocompromised patients. It accelerates lung disease and causes necrotizing pneumonia with associated severe sepsis, known as cepacia syndrome. In particular, lung transplant recipients infected with Burkholderia cepacia show higher mortality after lung transplantation than those who are not infected with this organism. Due to broad-spectrum antibiotic resistance, a combination therapy should be used according to the results of the susceptibility test. This bacterial infection is rare in Korea, and no case was reported in lung transplant recipients. However, we report a case of pneumonia caused by Burkholderia cepacia after lung transplantation. As Burkholderia cepacia was grown from a sputum culture, the patient was treated initially with a combination of meropenem and trimethoprim/sulfamethoxazole and then ceftazidime and trimethoprim/sulfamethoxazole as a result of leukopenia. After antibiotics treatment for 20 days, sputum cultures became negative for Burkholderia cepacia and the patient successfully recovered.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Koh, Shin Ok(고신옥)
Na, Sungwon(나성원) ORCID logo https://orcid.org/0000-0002-1170-8042
Park, Moo Suk(박무석) ORCID logo https://orcid.org/0000-0003-0820-7615
Paik, Hyo Chae(백효채) ORCID logo https://orcid.org/0000-0001-9309-8235
Lee, Bahn(이반)
Cho, Jin Sun(조진선) ORCID logo https://orcid.org/0000-0002-5408-4188
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