4 87

Cited 11 times in

Predictive factors for pregnancy during the first four intrauterine insemination cycles using gonadotropin

Authors
 Seok Kyo Seo ; Young Eun Jeon ; Byung Seok Lee ; Young Sik Choi ; SiHyun Cho ; Hye Yeon Kim ; Ji Ann Jung 
Citation
 Gynecological Endocrinology , Vol.29(9) : 834~838, 2013 
Journal Title
 Gynecological Endocrinology 
ISSN
 0951-3590 
Issue Date
2013
Abstract
PURPOSE: Although a variety of factors have been reported as affecting pregnancy rates after intrauterine insemination (IUI), there have been conflicting results on prognostic factors. This study aimed to determine predictive factors for pregnancy in patients undergoing the first four IUI cycles. METHODS: A total of 348 IUI cycles using clomiphene citrate or letrozole combined with gonadotropin, or gonadotropin only were analyzed. Baseline clinical characteristics, variables related to ovulation induction and sperm parameters were compared between pregnant (n = 54) and non-pregnant groups (n = 294). Logistic regression analysis was performed to identify factors that could predict a pregnancy. RESULTS: The overall clinical pregnancy rate was 15.5% (54/348) per cycle and 30.0% (54/180) per couple. During the first four IUI cycles, logistic regression analysis revealed that woman who were 39 years or older (OR: 0.263, 95% CI: 0.076-0.906, p = 0.034), longer duration of infertility (OR: 0.967, 95% CI: 0.942-0.993, p = 0.012), endometriosis (versus unexplained infertility; OR: 0.177, 95% CI: 0.040-0.775, p = 0.022) and endometrial thickness below 7 mm (OR: 0.114, 95% CI: 0.015-0.862, p = 0.035) were unfavorable factors to predict clinical pregnancy. CONCLUSIONS: Women with old age, longer duration of infertility, the presence of endometriosis or thin endometrium in the preovulatory phase may have unfavorable outcomes during the first four IUI cycles.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87815
DOI
10.3109/09513590.2013.808324
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Obstetrics & Gynecology
Yonsei Authors
사서에게 알리기
  feedback
Link
 http://informahealthcare.com/doi/abs/10.3109/09513590.2013.808324
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse