7 425

Cited 9 times in

18F-fluorodeoxyglucose positron emission tomography–computed tomography for the evaluation of bone metastasis in patients with gastric cancer

 Dae Won Ma  ;  Jie-Hyun Kim  ;  Tae Joo Jeon  ;  Yong Chan Lee  ;  Mijin Yun  ;  Young Hoon Youn  ;  Hyojin Park  ;  Sang In Lee 
 DIGESTIVE AND LIVER DISEASE, Vol.45(9) : 769-775, 2013 
Journal Title
Issue Date
Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/secondary* ; Bone and Bones/diagnostic imaging ; Female ; Fluorodeoxyglucose F18 ; Humans ; Male ; Middle Aged ; Multimodal Imaging* ; Positron-Emission Tomography ; Radiopharmaceuticals ; Retrospective Studies ; Sensitivity and Specificity ; Stomach Neoplasms/pathology* ; Tomography, X-Ray Computed
(18)F-FDG PET–CT ; Bone metastasis ; Gastric cancer ; WBBS
BACKGROUND: The roles of positron emission tomography and bone scanning in identifying bone metastasis in gastric cancer are unclear. AIM: We compared the usefulness of positron emission tomography-computed tomography and scanning in detecting bone metastasis in gastric cancer. METHODS: Data from 1485 patients diagnosed with gastric cancer who had undergone positron emission tomography-computed tomography and scanning were reviewed. Of 170 enrolled patients who were suspected of bone metastasis in either positron emission tomography or scanning, 81.2% were confirmed to have bone metastasis. RESULTS: The sensitivity, specificity, and accuracy were 93.5%, 25.0%, and 80.6%, respectively, for positron emission tomography and 93.5%, 37.5%, and 82.9%, respectively, for scanning. 87.7% of patients with bone metastasis showed positive findings on two modalities. 15.0% of solitary bone metastases were positive on positron emission tomography only. Positron emission tomography was superior to scanning for the detection of synchronous bone metastasis, but the two modalities were similar for the detection of metachronous bone metastasis. The concordance rate of response assessment after treatment between two modalities was moderate. CONCLUSIONS: Positron emission tomography-computed tomography may be more effective for the diagnosis of bone metastasis in the initial staging workup. Conversely, bone scanning and positron emission tomography-computed tomography may be similarly effective for the detection of metachronous bone metastasis.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jie-Hyun(김지현) ORCID logo https://orcid.org/0000-0002-9198-3326
Park, Hyo Jin(박효진) ORCID logo https://orcid.org/0000-0003-4814-8330
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
Youn, Young Hoon(윤영훈) ORCID logo https://orcid.org/0000-0002-0071-229X
Lee, Yong Chan(이용찬) ORCID logo https://orcid.org/0000-0001-8800-6906
Jeon, Tae Joo(전태주) ORCID logo https://orcid.org/0000-0002-7574-6734
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.