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Diverse left ventricular morphology and predictors of short-term outcome in patients with stress-induced cardiomyopathy

 Sung Woo Kwon  ;  Byung Ok Kim  ;  Myung-Hyun Kim  ;  Sung-Joo Lee  ;  Ji Hyun Yoon  ;  Hyemoon Chung  ;  Chi-Young Shim  ;  Duk Kyu Cho  ;  Sung Kee Ryu  ;  Se-Jung Yoon  ;  Young Won Yoon  ;  Hyuk-Jae Chang  ;  Se-Joong Rim  ;  Hyuck Moon Kwon  ;  Yangsoo Jang  ;  Bum-Kee Hong 
 International Journal of Cardiology, Vol.168(1) : 331-337, 2013 
Journal Title
 International Journal of Cardiology 
Issue Date
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Female ; Heart Ventricles/diagnostic imaging* ; Hospital Mortality/trends* ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Republic of Korea/epidemiology ; Takotsubo Cardiomyopathy/diagnostic imaging* ; Takotsubo Cardiomyopathy/mortality* ; Treatment Outcome ; Ultrasonography ; Young Adult
Echocardiography ; Hospital mortality ; Prognosis ; Takotsubo cardiomyopathy
BACKGROUND: There is paucity of data with regard to the clinical spectrum according to left ventricle (LV) morphological variation in stress-induced cardiomyopathy (SCMP) patients, and still there is controversy in terms of prognosis since some people believe that the published in-hospital mortality data of patients with SCMP are underestimated. Therefore, we sought to investigate the morphological features of LV and in-hospital outcome of patients with SCMP and explored predictors of short-term prognosis. METHODS: This was a multicenter, observational study of 208 SCMP patients. Morphological features of LV were determined by echocardiography and were divided into typical (apical) and atypical ballooning types, which were subcategorized into mid-LV ballooning and basal 'inverted' ballooning type. All-cause mortality of patients with SCMP during hospitalization was recorded. RESULTS: The apical ballooning type was most common (67.3%) in SCMP followed by the mid-LV ballooning type (28.3%), and the basal 'inverted' ballooning type (4.3%). There were no differences in stressor types and in-hospital mortality between patients with typical and atypical SCMP. Notably, all the in-hospital mortality of SCMP patients occurred in patients with physical stressors, where age, shock, and LV ejection fraction were the independent risk factors for predicting in-hospital mortality. CONCLUSIONS: SCMP patients showed diverse patterns of LV morphology, but there were no definite differences on clinical spectrum among SCMP patients presenting various LV morphological patterns. In terms of short-term prognosis, underlying physical conditions combined with old age, hemodynamic compromise, and low LV systolic function might be the most important factors in SCMP patients.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Sung Woo(권성우)
Kwon, Hyuck Moon(권혁문) ORCID logo https://orcid.org/0000-0001-9901-5015
Kim, Myung Hyun(김명현)
Shim, Chi Young(심지영) ORCID logo https://orcid.org/0000-0002-6136-0136
Yoon, Young Won(윤영원) ORCID logo https://orcid.org/0000-0002-0907-0350
Yoon, Ji Hyun(윤지현)
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Hye Moon(정혜문)
Hong, Bum Kee(홍범기) ORCID logo https://orcid.org/0000-0002-6456-0184
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