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Diverse left ventricular morphology and predictors of short-term outcome in patients with stress-induced cardiomyopathy

 Hyemoon Chung ; Sung Woo Kwon ; Bum-Kee Hong ; Yangsoo Jang ; Hyuck Moon Kwon ; Se-Joong Rim ; Hyuk-Jae Chang ; Young Won Yoon ; Se-Jung Yoon ; Sung Kee Ryu ; Duk Kyu Cho ; Chi-Young Shim ; Ji Hyun Yoon ; Sung-Joo Lee ; Myung-Hyun Kim ; Byung Ok Kim 
 International Journal of Cardiology, Vol.168(1) : 331~337, 2013 
Journal Title
 International Journal of Cardiology 
Issue Date
BACKGROUND: There is paucity of data with regard to the clinical spectrum according to left ventricle (LV) morphological variation in stress-induced cardiomyopathy (SCMP) patients, and still there is controversy in terms of prognosis since some people believe that the published in-hospital mortality data of patients with SCMP are underestimated. Therefore, we sought to investigate the morphological features of LV and in-hospital outcome of patients with SCMP and explored predictors of short-term prognosis. METHODS: This was a multicenter, observational study of 208 SCMP patients. Morphological features of LV were determined by echocardiography and were divided into typical (apical) and atypical ballooning types, which were subcategorized into mid-LV ballooning and basal 'inverted' ballooning type. All-cause mortality of patients with SCMP during hospitalization was recorded. RESULTS: The apical ballooning type was most common (67.3%) in SCMP followed by the mid-LV ballooning type (28.3%), and the basal 'inverted' ballooning type (4.3%). There were no differences in stressor types and in-hospital mortality between patients with typical and atypical SCMP. Notably, all the in-hospital mortality of SCMP patients occurred in patients with physical stressors, where age, shock, and LV ejection fraction were the independent risk factors for predicting in-hospital mortality. CONCLUSIONS: SCMP patients showed diverse patterns of LV morphology, but there were no definite differences on clinical spectrum among SCMP patients presenting various LV morphological patterns. In terms of short-term prognosis, underlying physical conditions combined with old age, hemodynamic compromise, and low LV systolic function might be the most important factors in SCMP patients.
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1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
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