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가와사키병과 Immunoglobulin E의 관계

Other Titles
 Relation between Kawasaki Disease and Immunoglobulin E 
 구청모  ;  최성열  ;  김동수  ;  김기환 
 Journal of Rheumatic Diseases, Vol.20(1) : 4-8, 2013 
Journal Title
 Journal of Rheumatic Diseases 
Issue Date
Kawasaki disease ; Immunoglobulin E
Objective Kawasaki disease is a systemic vascular disease which is caused by an immunologic response. The purpose of this study is to see how a high IgE level affects Kawasaki disease, in two groups of high IgE level and low IgE level. Methods A retrospective study was done from 2008 to 2010, among patients, who were admitted in Severance Children's Hospital for Kawasaki disease with IgE levels checked. Age groups with an IgE level above reference ranges and those with normal ranges were done. Also, clinical characteristics were analyzed. Statistical method was done by SPSS 18. Results A total of 198 Kawasaki patients were analyzed from 2008 to 2010. Among them 123 (62%) patients showed elevated IgE levels. Patients with high IgE had a significantly higher lymphadenopathy prevalence (p=0.006), however they had no connection with quantitative values. Patients with BCG site redness appeared to have lower IgE levels than patients without redness. Coronary complication had no relation with IgE levels. There was no correlation between laboratory results and IgE levels. Conclusion 62% of Kawasaki disease patients show high IgE levels in our study. The symptoms of BCG site redness aged less than 1 year seemed to be related with IgE level. To understand the pathophysiology of Kawasaki disease, more studies should be performed on the role of IgE.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ki Hwan(김기환)
Kim, Dong Soo(김동수)
Choi, Seong Yeol(최성열)
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