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Reevaluation of Patients With Bipolar Disorder on Manic Episode : Improving the Diagnosing of Mixed Episode

Authors
 Kyung Ran Kim ; Hyun-Sang Cho ; Duk-In Jon ; Eun Lee ; Jeong-Ho Seok ; Se Joo Kim 
Citation
 Journal of Nervous and Mental Disease, Vol.201(8) : 686~690, 2013 
Journal Title
 Journal of Nervous and Mental Disease 
ISSN
 0022-3018 
Issue Date
2013
Abstract
Abstract: Mixed manic/depressive episodes in patients with bipolar disorder are underdiagnosed because of restrictive diagnostic criteria. Using the broader definition of a mixed episode represented by the Cincinnati criteria, we reevaluated the medical records of patients with bipolar disorder hospitalized for a manic episode. We also examined the predictive power of previously unrecognized depressive symptoms. Of 520 inpatients with mania, we retrospectively diagnosed 59 (11.3%) as having a probable mixed episode. Compared with the patients with pure mania, the patients with mixed episodes were more likely to have a family history of psychiatric illness, comorbid personality disorder, and a history of suicide attempts. Binary logistic regression revealed that loss of interest, loss of energy, feelings of worthlessness, and feelings of helplessness had good positive predictive value (>0.7) for mixed episodes. Accurate diagnosis of mixed episodes may require a broadening of diagnostic criteria and emphasis on symptoms such as loss of interest, loss of energy, and feelings of worthlessness and helplessness.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87374
DOI
10.1097/NMD.0b013e31829c505a
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Psychiatry
Yonsei Authors
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Link
 http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00005053-201308000-00007&LSLINK=80&D=ovft
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