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Reevaluation of Patients With Bipolar Disorder on Manic Episode : Improving the Diagnosing of Mixed Episode

Authors
 Kyung Ran Kim  ;  Hyun-Sang Cho  ;  Duk-In Jon  ;  Eun Lee  ;  Jeong-Ho Seok  ;  Se Joo Kim 
Citation
 Journal of Nervous and Mental Disease, Vol.201(8) : 686-690, 2013 
Journal Title
 Journal of Nervous and Mental Disease 
ISSN
 0022-3018 
Issue Date
2013
Abstract
Abstract: Mixed manic/depressive episodes in patients with bipolar disorder are underdiagnosed because of restrictive diagnostic criteria. Using the broader definition of a mixed episode represented by the Cincinnati criteria, we reevaluated the medical records of patients with bipolar disorder hospitalized for a manic episode. We also examined the predictive power of previously unrecognized depressive symptoms. Of 520 inpatients with mania, we retrospectively diagnosed 59 (11.3%) as having a probable mixed episode. Compared with the patients with pure mania, the patients with mixed episodes were more likely to have a family history of psychiatric illness, comorbid personality disorder, and a history of suicide attempts. Binary logistic regression revealed that loss of interest, loss of energy, feelings of worthlessness, and feelings of helplessness had good positive predictive value (>0.7) for mixed episodes. Accurate diagnosis of mixed episodes may require a broadening of diagnostic criteria and emphasis on symptoms such as loss of interest, loss of energy, and feelings of worthlessness and helplessness.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/87374
DOI
10.1097/NMD.0b013e31829c505a
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실)
Yonsei Authors
김경란(Kim, Kyung Ran) ; 김세주(Kim, Se Joo) ; 석정호(Seok, Jeong Ho) ; 이은(Lee, Eun) ; 조현상(Cho, Hyun Sang)
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