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Dissimilarity of femur aging in men and women from a Nationwide Survey in Korea (KNHANES IV)

 Kyoung Min Kim  ;  Jung Soo Lim  ;  Kwang Joon Kim  ;  Han Seok Choi  ;  Yumie Rhee  ;  Han Jin Oh  ;  Hoon Choi  ;  Woong Hwan Choi  ;  Jung Gu Kim  ;  Sung-Kil Lim 
 Journal of Bone and Mineral Metabolism, Vol.31(2) : 144-152, 2013 
Journal Title
 Journal of Bone and Mineral Metabolism 
Issue Date
In light of the differences in hip fracture rates between men and women of different ages, age-related changes in bone structure that lead to bone fragility might differ depending on both age and gender. To investigate age-related bone loss and geometric deterioration of the femur, hip scans of 1,504 men and 2,076 women aged 19-92 years acquired during the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV) using dual-energy X-ray absorptiometry (DXA) were analyzed with a structural analysis program. Cross-sectional area and cortical thickness with bone mineral density in men started to decline from the third decade and continued to decline at a constant rate. However, in women, these parameters remained nearly constant until the fifth decade and then declined at a more rapid rate than that seen in men. Consequently, changes in the buckling ratio, earlier onset, and continuation of increase over the lifetime were observed in men. A relatively later onset with a greater acceleration with aging was observed in women. Taken together, there were obvious gender and age differences in structural trends with age. Bone aging, i.e., bone loss and geometric deterioration, actually begins at a young age, especially in men, and osteoporosis prevention strategies should target not only the elderly but also younger individuals.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김경민(Kim, Kyung Min)
김광준(Kim, Kwang Joon) ORCID logo https://orcid.org/0000-0002-5554-8255
이유미(Rhee, Yumie) ORCID logo https://orcid.org/0000-0003-4227-5638
임승길(Lim, Sung Kil)
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