Subfertility is a prevalent problem and has significant consequences for individual, families, and with wider community. Currently, there are no uniform counseling guidelines or evidence-based recommendation available. People’s chances of having a healthy, live birth may be affected by factors such as age, weight, diet, smoking, other substances, environmental factors, medical conditions, medications and family medical history. This review focuses on the impact of potentially modifiable lifestyle factors affecting fertility in the general population and the infertile population. Advice on modifiable lifestyle factors should be given to people considering a family or presenting for infertility treatment may improve their chances of conception and delivering a healthy, live baby.