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How is the peri-patch myocardium in ventricular septal defect patch repair?

 Lucy Youngmin Eun  ;  Han Ki Park  ;  Jae Young Choi 
 Journal of Cardiology, Vol.61(5) : 354-358, 2013 
Journal Title
 Journal of Cardiology 
Issue Date
Child, Preschool ; Echocardiography, Doppler, Color ; Heart Septal Defects, Ventricular/diagnostic imaging ; Heart Septal Defects, Ventricular/physiopathology* ; Heart Septal Defects, Ventricular/surgery* ; Humans ; Infant ; Infant, Newborn ; Myocardial Contraction/physiology*
Tissue Doppler echocardiography ; StrainPeri-patch region ; Myocardial function
Strain rate (SR) and strain (≈) in tissue Doppler imaging provide new noninvasive measurements of myocardial function, independent of heart motion. This study assesses the extent of peri-patch regional myocardial function after patch repair of ventricular septal defect (VSD). Myocardial SR and ≈ were recorded from the peri-patch myocardium and remote septum from patch area in 18 patients (1 month to 4 years of age, mean 2.3 years). Distance between the patch and the point of returning to remote normal strain (≈) profile was measured. Compared to the remote myocardial region, peri-patch myocardium had decreased peak longitudinal SR (-3.8 ± 2.1s(-1) vs. -5.3 ± 3.3s(-1), p<0.05), delayed time to peak longitudinal SR (144 ± 59 ms vs. 110 ± 46 ms, p<0.05), decreased peak ≈ (longitudinal, -20.8 ± 8.1% vs. -28.7 ± 11.1%; radial, 20.1 ± 16.3% vs. 34.3 ± 22.4%, p<0.01), and delayed time to peak ≈ (longitudinal, 314 ± 80 ms vs. 241 ± 63 ms; radial, 329 ± 99 ms vs. 265 ± 78 ms, p<0.0001). The mean distance from the patch to the remote patch ɛ curve was 2.55 ± 0.77 mm. CONCLUSION: Peri-patch myocardium after repair of VSD has delayed and diminished contraction as compared to more remote normal myocardium.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Park, Han Ki(박한기) ORCID logo https://orcid.org/0000-0002-7472-7822
Eun, Lucy Youngmin(은영민) ORCID logo https://orcid.org/0000-0002-4577-3168
Choi, Jae Young(최재영) ORCID logo https://orcid.org/0000-0002-1247-6669
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