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Arterial ageing

Authors
 Seung-Jun Lee  ;  Sung-Ha Park 
Citation
 Korean Circulation Journal, Vol.43(2) : 73-79, 2013 
Journal Title
 Korean Circulation Journal 
ISSN
 1738-5520 
Issue Date
2013
Abstract
Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on hypertension, the renin-angiotensin-aldosterone system and vascular inflammation which are modifiable causes of the arterial ageing process. Also, novel treatment targets derived from the disease models such as the Hutchinson Gilford Progeria Syndrome were reviewed.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86533
DOI
10.4070/kcj.2013.43.2.73
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
박성하(Park, Sung Ha)
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