Higher-order aberrations and visual outcomes of a new refractive extended depth-of-focus intraocular lens with a target of slight myopia

Abstract

In this single-center retrospective study, we compared visual performance and optical quality between a new refractive extended depth-of-focus intraocular lens (EDoF IOL, Model ZEN00V, n = 44), with a slightly myopic target, and an enhanced monofocal IOL (Model ICB00, n = 44), with the target refraction closest to emmetropia on the myopic side. The IOL power for the EDoF IOL was selected to achieve postoperative refraction of -0.50 to -1.00 D. Monocular distance visual acuity (VA) and iTrace aberrometry were assessed. Bilateral cases were analyzed to evaluate intermediate and near VA, and photic phenomena. Preoperative target diopter and postoperative spherical equivalent were more myopic in the EDoF IOL group than in the monofocal IOL group (all p < 0.001). Uncorrected and corrected distance VA were comparable between the two groups (all p > 0.05). Higher order aberrations were comparable between the two groups (all p > 0.05) except for spherical aberrations, which were lower in the monofocal group (p = 0.002). Subgroup analysis revealed superior near VA (p = 0.02) and an extended range of defocus in the EDoF IOL group with comparable photic phenomena. Implantation of the new refractive EDoF IOL, the TECNIS PureSee (TM), with myopic target diopter may be a viable option for improving intermediate and near visual performance while preserving distance vision and visual quality.