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The Role of Medical Therapy in Hypertrophic Card iomyopathy An Updated Review

Authors
 Lee, Jung-Won  ;  Chun, Kyeong-Hyeon  ;  Choi, Eui-Young  ;  Seo, Jiwon 
Citation
 HEART FAILURE CLINICS, Vol.21(4) : 549-558, 2025-10 
Journal Title
HEART FAILURE CLINICS
ISSN
 1551-7136 
Issue Date
2025-10
MeSH
Adrenergic beta-Antagonists / therapeutic use ; Calcium Channel Blockers / therapeutic use ; Cardiomyopathy, Hypertrophic* / drug therapy ; Humans
Keywords
Hypertrophic cardiomyopathy ; Myosin inhibitors ; Medical therapy
Abstract
The perception of HCM has shifted from a disease leading to sudden death to a condition requiring lifelong management. Given its relatively high prevalence and the need for ongoing treatment, the medication-based management of symptoms and comorbidities in these patients is crucial (Fig. 4). Research on the pathophysiology and genetic characteristics of HCM is ongoing, and new mechanism-based drugs are continually being developed. Therefore, an appropriate application of pharmacotherapy, considering the individual characteristics of each patient, is important. Additionally, patient education and lifestyle management should be integrated to achieve the sustained effectiveness of medical therapy. Ongoing drug development underscores the importance of health care providers staying regularly informed about emerging therapies.
Full Text
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S1551713625000546
DOI
10.1016/j.hfc.2025.06.005
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Seo, Jiwon(서지원) ORCID logo https://orcid.org/0000-0002-7641-3739
Lee, Jung-Won(이정원)
Chun, Kyeong Hyeon(전경현) ORCID logo https://orcid.org/0000-0002-7798-658X
Choi, Eui Young(최의영) ORCID logo https://orcid.org/0000-0003-3732-0190
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/209229
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