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The international expert consensus on management of external auditory canal carcinoma

Authors
 Zhou, Pei  ;  de Brito, Rubens  ;  Cui, Yong  ;  Lloyd, Simon  ;  Kunst, Henricus  ;  Kutz, J. Walter  ;  Mani, Navin  ;  Moon, In Seok  ;  Mostafa, Badr Eldin  ;  Nabuurs, Cindy  ;  Rao, Sampath Chandra Prasad  ;  Xie, Bingbin  ;  Zhang, Yibo  ;  Dai, Chunfu 
Citation
 EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, Vol.282(4) : 1677-1691, 2025-04 
Journal Title
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
ISSN
 0937-4477 
Issue Date
2025-04
MeSH
Carcinoma* / pathology ; Carcinoma* / therapy ; Combined Modality Therapy ; Consensus ; Ear Canal* / pathology ; Ear Canal* / surgery ; Ear Neoplasms* / diagnosis ; Ear Neoplasms* / pathology ; Ear Neoplasms* / therapy ; Humans ; Neoplasm Staging
Keywords
External auditory canal carcinoma ; Clinical practice guidelines ; Temporal bone ; Expert consensus
Abstract
PurposeThe objective of this consensus is to provide otolaryngologists with appropriate strategies in the management of external auditory canal (EAC) carcinoma.MethodsIn the absence of randomized controlled trials, the consensus is based on expert opinions utilizing the Rand/UCLA appropriateness method [Fitch and Aguilar in The RAND/UCLA appropriateness method user's manual, RAND Corporation, Santa Monica, CA, 2001], drawing from existing literature and clinical experience.ResultsThe management recommendations are structured around 12 key areas, including: definition and pathology, pathogenesis, clinical manifestations, work-up, tumor staging system, surgical management of primary tumor, surgical management of the parotid gland and the temporomandibular joint, lymph node metastasis, radiotherapy, chemotherapy, reconstruction, and follow-up.ConclusionManagement strategies for EAC carcinoma rely on tumor extension and histopathological features. Surgical removal with free surgical margins or combination with radiotherapy, chemotherapy are most often the best options. Given the rarity of the disease, prospective, randomized, multi-institutional clinical trials should be designed to enable reliable comparisons of the outcomes of EAC carcinoma treatments, thereby providing evidence-based clinical data to establish widely accepted guidelines. It emphasizes the need for a multidisciplinary team to be involved in the management of EAC carcinoma, and regular follow-up should be implemented postoperatively.
Full Text
https://link.springer.com/article/10.1007/s00405-024-09033-w
DOI
10.1007/s00405-024-09033-w
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Moon, In Seok(문인석) ORCID logo https://orcid.org/0000-0002-3951-5074
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/209029
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