Evaluating Poly-D,L-Lactic Acid for Lower Eyelid Rejuvenation: Efficacy and Safety

Abstract

Background Injectable fillers like PDLLA offer a novel approach to addressing lower eyelid rejuvenation. Despite their growing popularity, comprehensive studies on newer products like PDLLA are limited. Aims This study evaluates the efficacy and safety of PDLLA (Juvelook, VAIM Inc., Seoul, Korea) for treating tear trough deformities in Korean women, aiming to provide a long-term, minimally invasive solution for periorbital rejuvenation. Materials & Methods A selected group of Korean women exhibiting tear trough deformities underwent treatment with PDLLA. Patients were assessed pre-treatment and followed up at 1 week, 1 month, and 6 months post-treatment, with outcomes measured by independent clinicians using the Hirmand classification and patient satisfaction scores. Results PDLLA demonstrated significant improvements in tear trough deformities with high patient satisfaction and minimal adverse effects. Follow-up results showed sustained improvements and no severe complications, indicating a safe profile for PDLLA. Discussion The study highlights PDLLA's potential advantages over traditional fillers, including longer-lasting effects and enhanced collagen production, suggesting it as a superior option for those seeking durable aesthetic improvements. Conclusion PDLLA is an effective and safe treatment for periorbital rejuvenation in Korean women, providing lasting benefits and high patient satisfaction, warranting further comparative studies for broader applications.