항암 치료로 인한 말초신경병증을 경험하는 암 환자의 삶의 질 관련 요인: 주제범위 문헌고찰

Abstract

Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of chemotherapy, leading to disturbances in everyday life, reduced treatment adherence, and impaired quality of life (QoL). This study aimed to identify factors related to the QoL of cancer patients with CIPN. Methods: This scoping review was conducted using the JBI methodology. Literature published between January 2014 and April 2024 was searched in various databases, including PubMed, Embase, CINAHL, Cochrane Library, KoreaMed, and RISS. The target population consisted of cancer patients experiencing CIPN, the concept focused on the factors associated with QoL, and the context included both hospitalization and post-discharge periods. Results: A total of 18 studies were reviewed. The factors identified in descriptive and correlational studies were categorized into five domains: physical, psychological, functional, diagnosis/treatment, and general characteristics. The most frequently explored domain was the psychological domain (consisting of psychological distress, negative emotions, and optimism), and the Hospital Anxiety Depression Scale (HADS) was the most frequently used instrument. The functional domain, which included self-care ability and activities of daily living (ADL), was also frequently studied, with the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool (CIPNAT) being the primary instrument used. The factors derived from the experimental studies were the provision of intervention (exercise and self-acupressure) and the timing of the intervention (before or after chemotherapy). Conclusion: Based on these findings, it is recommended that nurses address these factors when caring for patients with CIPN. Additionally, it is essential to develop interventions to manage psychological symptoms and ADL. Further studies are required to validate the effects of interventions on the QoL of patients with CIPN and their clinical application.