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Long Term Survivor of Stage IV Pancreatic Adenocarcinoma: A Case Report

Authors
 Jinny Lee  ;  Eun Hye Song  ;  Hyung Sun Kim 
Citation
 Clinics in Medicine, Vol.6 : 1064, 2024-07 
Journal Title
Clinics in Medicine
Issue Date
2024-07
Keywords
Pancreatic adenocarcinoma ; Long term survivor ; Stage IV ; Case report
Abstract
Introduction: Pancreatic cancer presents a significant public health challenge in Korea, with an increasing incidence rate in recent years. The prognosis of
pancreatic cancer in Korea is poor, marked by a 5-year survival rate of only 9.5%. Stage IV pancreatic cancer, in particular, carries an exceptionally poor prognosis,
with a median survival period of 3 to 6 months. Here, we present a case of a patient with stage IV pancreatic adenocarcinoma with an unusual survival time of
34 months after initial diagnosis.
Case presentation: Our patient, an 80-year-old Korean woman, received her initial pancreatic cancer diagnosis in August 2019. The initial CT scan revealed
that the cancer had invaded the head of the pancreas as well as the superior mesenteric vein, splenic vein, and main portal vein. Additionally, there was a
strong suspicion of seeding metastasis, leading to the exclusion of surgery. The medical team administered approximately 20 cycles of gemcitabine/nab-paclitaxel
combination as palliative chemotherapy, according to the Korean Pancreatic Cancer treatment recommendations. Following subsequent palliative chemotherapy,
the patient’s CA19-9 levels immediately decreased and remained stable, with occasional fluctuations occurring after the interruption of chemotherapy. The patient
declined further chemotherapy after the completion of the 20th cycle in November 2021. Alongside the cancer diagnosis, the patient was also diagnosed with
chronic cholangitis with common bile duct stones, liver abscess, and acute enter colitis. In June 2022, the patient was admitted for a final visit due to abdominal
pain caused by acute gastroenteritis. With a deteriorating condition, the patient requested a transfer to a local hospital for hospice care and died approximately
34 months after the initial diagnosis.
Conclusion: The patient’s initial sensitivity and lack of resistance to chemotherapy as well as good nutrition and physical health seemed to be the main contributors
to the patient’s exceptional survival.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyung Sun(김형선) ORCID logo https://orcid.org/0000-0002-9002-3569
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/200588
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