Immune Reconstitution Inflammatory Syndrome-Like Reaction During the Treatment of Pneumocystis jirovecii Pneumonia in an Infant With Severe Combined Immunodeficiency

Abstract

The effectiveness of corticosteroids in preventing immune reconstitution inflammatory syndrome in non-human immunodeficiency viruses Pneumocystis carinii pneumonia (PCP) patients, such as severe combined immunodeficiency (SCID) patients, is controversial. We experienced a paradoxical reaction during severe PCP treatment in a SCID infant, which responded well to adjuvant corticosteroids.