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Association between Muscle Mass Index and Neurological Outcomes of Patients with Out-of-Hospital Cardiac Arrest

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dc.contributor.author박유석-
dc.contributor.author유제성-
dc.contributor.author조용탁-
dc.contributor.author한민경-
dc.date.accessioned2024-06-14T03:09:39Z-
dc.date.available2024-06-14T03:09:39Z-
dc.date.issued2024-05-
dc.identifier.issn0024-3019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/199794-
dc.description.abstractMuscle mass depletion is associated with unfavorable outcomes in many diseases. However, its relationship with cardiac arrest outcomes has not been explored. This retrospective single-center study determined the relationship between muscle mass depletion and the neurological outcomes of patients with out-of-hospital cardiac arrest (OHCA) by measuring muscle mass at various locations. Adult patients with OHCA, who were treated with target temperature management, and who underwent abdominal or chest computed tomography (CT) within 3 months of the cardiac arrest were included. Skeletal muscle index (SMI) was measured at the third lumbar vertebra (L3) level, psoas muscle, fourth thoracic vertebra (T4) level, and pectoralis muscle. The Youden index was used to determine a low SMI based on sex-specific cutoff values. The outcome variables were “good neurological outcome” and “survival” at hospital discharge. Multivariable analyses revealed that patients with low T4 SMI level were significantly associated with good neurological outcomes at hospital discharge (odds ratio = 0.26, 95% confidence interval: 0.07–0.88, p = 0.036). However, no significant differences were observed between good neurological outcomes and low SMI at the L3 level and psoas and pectoralis muscles; SMIs were not associated with survival at hospital discharge. T4 level SMI depletion was inversely associated with good neurological outcomes in patients with OHCA. Thoracic muscle depletion may be crucial for predicting the neurological outcomes in patients with OHCA and further investigation in larger prospective study is warranted.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherTime, Inc.-
dc.relation.isPartOfLife-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleAssociation between Muscle Mass Index and Neurological Outcomes of Patients with Out-of-Hospital Cardiac Arrest-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Emergency Medicine (응급의학교실)-
dc.contributor.googleauthorYongtak Cho-
dc.contributor.googleauthorEung Nam Kim-
dc.contributor.googleauthorJe Sung You-
dc.contributor.googleauthorMinkyung Han-
dc.contributor.googleauthorYoo Seok Park-
dc.identifier.doi10.3390/life14060680-
dc.contributor.localIdA01592-
dc.contributor.localIdA02507-
dc.contributor.localIdA06132-
dc.contributor.localIdA05436-
dc.relation.journalcodeJ03809-
dc.subject.keywordmuscle mass index-
dc.subject.keywordneurological outcome-
dc.subject.keywordout-of-hospital cardiac arrest-
dc.subject.keywordsarcopenia-
dc.subject.keywordcomputed tomography-
dc.contributor.alternativeNamePark, Yoo Seok-
dc.contributor.affiliatedAuthor박유석-
dc.contributor.affiliatedAuthor유제성-
dc.contributor.affiliatedAuthor조용탁-
dc.contributor.affiliatedAuthor한민경-
dc.citation.volume14-
dc.citation.number6-
dc.citation.startPage680-
dc.identifier.bibliographicCitationLife, Vol.14(6) : 680, 2024-05-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers

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