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A practical review of watch-and-wait approach in rectal cancer

Authors
 Hwa Kyung Byun  ;  Woong Sub Koom 
Citation
 RADIATION ONCOLOGY JOURNAL, Vol.41(1) : 4-11, 2023-03 
Journal Title
RADIATION ONCOLOGY JOURNAL
ISSN
 2234-1900 
Issue Date
2023-03
Keywords
Non-operative management ; Rectal neoplasms ; Watch and wait
Abstract
Rectal resection surgery after neoadjuvant treatment has been the mainstay treatment of locally advanced rectal cancer. However, functional outcomes and quality of life after radical resection of the rectum remain suboptimal. The excellent oncologic outcomes in patients who achieved pathologic complete response after neoadjuvant treatment questioned the need for radical surgery. The watchand-wait approach is a noninvasive therapeutic alternative for organ preservation and avoiding operative morbidity. In the watch-and-wait approach, patients with locally advanced rectal cancer who achieve excellent clinical response after neoadjuvant treatment undergo active surveillance rather than rectal cancer surgery. In this practical review, we summarized the main results of studies on the watch-and-wait approach and provided a practical method for implementing the watch-and-wait approach.
Files in This Item:
T992023378.pdf Download
DOI
10.3857/roj.2023.00038
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Koom, Woong Sub(금웅섭) ORCID logo https://orcid.org/0000-0002-9435-7750
Byun, Hwa Kyung(변화경) ORCID logo https://orcid.org/0000-0002-8964-6275
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/199643
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