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Neck Circumference as a Predictor of Insulin Resistance in People with Non-alcoholic Fatty Liver Disease
DC Field | Value | Language |
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dc.contributor.author | 손다혜 | - |
dc.date.accessioned | 2024-05-30T06:53:14Z | - |
dc.date.available | 2024-05-30T06:53:14Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 2508-6235 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199418 | - |
dc.description.abstract | Background: Insulin resistance is common in individuals with non-alcoholic fatty liver disease (NAFLD). Because insulin resistance is a predictive factor for advanced liver diseases in people with NAFLD, efforts have been made to predict it through anthropometric variables. Recently, neck circumference (NC) has been regarded as a reliable alternative marker for metabolic disorders. This study verified the association between NC and insulin resistance in patients with NAFLD.Methods: We analyzed data from 847 people with NAFLD who participated in the 2019 Korean National Health and Nutrition Examination Survey. NAFLD was defined by a hepatic steatosis index score of >= 36 points, and insulin resistance was defined by a homeostatic model assessment of insulin resistance score of >= 2.5 points. Participants were divided according to sex-specific NC tertiles (T1, lowest; T2, middle; T3, highest).Results: In the analysis of the area under the receiver operating characteristic curve (AUC), NC displayed a greater predictive power than body mass index (BMI) for insulin resistance in women (AUC of NC=0.625 vs. AUC of BMI=0.573, P=0.035). NC and the odds ratio (OR) for insulin resistance showed a cubic relationship in both men and women. In the weighted multiple logistic regression analysis, the ORs with 95% confidence intervals for insulin resistance in people with NAFLD in T2 and T3 compared to the reference tertile (T1) were 1.06 (0.47-2.41) and 1.13 (0.41-3.11), respectively, in men and 1.12 (0.64-1.97) and 2.54 (1.19-5.39), respectively, in women, after adjusting for confounding factors.Conclusion: NC was positively correlated with insulin resistance in women with NAFLD. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society for the Study of Obesity | - |
dc.relation.isPartOf | JOURNAL OF OBESITY & METABOLIC SYNDROME | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Neck Circumference as a Predictor of Insulin Resistance in People with Non-alcoholic Fatty Liver Disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Da-Hye Son | - |
dc.contributor.googleauthor | Jee Hye Han | - |
dc.contributor.googleauthor | Jun-Hyuk Lee | - |
dc.identifier.doi | 10.7570/jomes22066 | - |
dc.contributor.localId | A05543 | - |
dc.relation.journalcode | J04125 | - |
dc.identifier.eissn | 2508-7576 | - |
dc.identifier.pmid | 37649143 | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Korean | - |
dc.subject.keyword | Neck circumference | - |
dc.subject.keyword | Non-alcoholic fatty liver disease | - |
dc.contributor.alternativeName | Son, Da‐Hye | - |
dc.contributor.affiliatedAuthor | 손다혜 | - |
dc.citation.volume | 32 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 214 | - |
dc.citation.endPage | 223 | - |
dc.identifier.bibliographicCitation | JOURNAL OF OBESITY & METABOLIC SYNDROME, Vol.32(3) : 214-223, 2023-09 | - |
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