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Transgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer

DC Field Value Language
dc.contributor.author박승우-
dc.contributor.author박정엽-
dc.contributor.author방승민-
dc.contributor.author송시영-
dc.contributor.author이희승-
dc.contributor.author정다운-
dc.contributor.author정문재-
dc.contributor.author조중현-
dc.date.accessioned2024-05-23T03:03:36Z-
dc.date.available2024-05-23T03:03:36Z-
dc.date.issued2024-03-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/199145-
dc.description.abstractBiliary tract cancer (BTC) is a relatively rare but aggressive gastrointestinal cancer with a high mortality rate. Cancer stem cell (CSC) populations play crucial roles in tumor biology and are responsible for the low response to anti-cancer treatment and the high recurrence rate. This study investigated the role of Transgelin-2 (TAGLN2), overexpressed in CSC in BTC cells, and analyzed its expression in patient tissues and serum to identify potential new targets for BTC.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfBMC CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHBiliary Tract Neoplasms* / drug therapy-
dc.subject.MESHBiliary Tract Neoplasms* / genetics-
dc.subject.MESHBiomarkers, Tumor / genetics-
dc.subject.MESHBiomarkers, Tumor / metabolism-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHHumans-
dc.subject.MESHMicrofilament Proteins* / genetics-
dc.subject.MESHMicrofilament Proteins* / metabolism-
dc.subject.MESHMuscle Proteins / genetics-
dc.titleTransgelin-2, a novel cancer stem cell-related biomarker, is a diagnostic and therapeutic target for biliary tract cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJung Hyun Jo-
dc.contributor.googleauthorSoo Been Park-
dc.contributor.googleauthorJoowon Chung-
dc.contributor.googleauthorTaeyun Oh-
dc.contributor.googleauthorHee Seung Lee-
dc.contributor.googleauthorMoon Jae Chung-
dc.contributor.googleauthorJeong Youp Park-
dc.contributor.googleauthorSeungmin Bang-
dc.contributor.googleauthorSeung Woo Park-
dc.contributor.googleauthorDawoon E Jung-
dc.contributor.googleauthorSi Young Song-
dc.identifier.doi10.1186/s12885-024-12082-3-
dc.contributor.localIdA01551-
dc.contributor.localIdA01647-
dc.contributor.localIdA01786-
dc.contributor.localIdA02035-
dc.contributor.localIdA03349-
dc.contributor.localIdA03587-
dc.contributor.localIdA03602-
dc.contributor.localIdA03912-
dc.relation.journalcodeJ00351-
dc.identifier.eissn1471-2407-
dc.identifier.pmid38509504-
dc.subject.keywordBiliary tract cancer-
dc.subject.keywordCancer stem cell-
dc.subject.keywordCancer-associated fibroblasts-
dc.subject.keywordTherapy-resistance-
dc.subject.keywordTransgelin-2-
dc.contributor.alternativeNamePark, Seung Woo-
dc.contributor.affiliatedAuthor박승우-
dc.contributor.affiliatedAuthor박정엽-
dc.contributor.affiliatedAuthor방승민-
dc.contributor.affiliatedAuthor송시영-
dc.contributor.affiliatedAuthor이희승-
dc.contributor.affiliatedAuthor정다운-
dc.contributor.affiliatedAuthor정문재-
dc.contributor.affiliatedAuthor조중현-
dc.citation.volume24-
dc.citation.number1-
dc.citation.startPage357-
dc.identifier.bibliographicCitationBMC CANCER, Vol.24(1) : 357, 2024-03-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
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