Cited 2 times in
Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial
DC Field | Value | Language |
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dc.contributor.author | 이동원 | - |
dc.date.accessioned | 2024-03-22T05:56:23Z | - |
dc.date.available | 2024-03-22T05:56:23Z | - |
dc.date.issued | 2023-08 | - |
dc.identifier.issn | 2093-2278 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/198299 | - |
dc.description.abstract | Purpose: Biphasic calcium phosphate (BCP), a widely used biomaterial for bone regeneration, contains synthetic hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), the ratio of which can be adjusted to modulate the rate of degradation. The aim of this study was to evaluate the clinical and radiographic benefits of reconstructing peri-implant bone defects with a newly developed BCP consisting of 60% β-TCP and 40% HA compared to demineralized bovine bone mineral (DBBM). Methods: This prospective, multicenter, parallel, single-blind randomized controlled trial was conducted at the periodontology departments of 3 different dental hospitals. Changes in clinical (defect width and height) and radiographic (augmented horizontal bone thickness) parameters were measured between implant surgery with guided bone regeneration (GBR) and re-entry surgery. Postoperative discomfort (severity and duration of pain and swelling) and early soft-tissue wound healing (dehiscence and inflammation) were also assessed. Data were compared between the BCP (test) and DBBM (control) groups using the independent t-test and the χ2 test. Results: Of the 53 cases included, 27 were in the test group and 26 were in the control group. After a healing period of 18 weeks, the full and mean resolution of buccal dehiscence defects were 59.3% (n=16) and 71.3% in the test group and 42.3% (n=11) and 57.9% in the control group, respectively. There were no significant differences between the groups in terms of the change in mean horizontal bone augmentation (test group: −0.50±0.66 mm vs. control groups: −0.66±0.83 mm, P=0.133), postoperative discomfort, or early wound healing. No adverse or fatal complications occurred in either group. Conclusions: The GBR procedure with the newly developed BCP showed favorable clinical, radiographic, postoperative discomfort-related, and early wound healing outcomes for periimplant dehiscence defects that were similar to those for DBBM. Trial Registration: Clinical Research Information Service Identifier: KCT0006428 | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Korean Academy of Periodontology | - |
dc.relation.isPartOf | JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Periodontics (치주과학교실) | - |
dc.contributor.googleauthor | Jae-Hong Lee | - |
dc.contributor.googleauthor | Hyun-Wook An | - |
dc.contributor.googleauthor | Jae-Seung Im 3 | - |
dc.contributor.googleauthor | Woo-Joo Kim | - |
dc.contributor.googleauthor | Dong-Won Lee | - |
dc.contributor.googleauthor | Jeong-Ho Yu | - |
dc.identifier.doi | 10.5051/jpis.2300640032 | - |
dc.contributor.localId | A02728 | - |
dc.relation.journalcode | J01695 | - |
dc.identifier.eissn | 2093-2286 | - |
dc.identifier.pmid | 37524378 | - |
dc.subject.keyword | Allografts | - |
dc.subject.keyword | Bone regeneration | - |
dc.subject.keyword | Bone substitutes | - |
dc.subject.keyword | Dental implants | - |
dc.subject.keyword | Randomized controlled trial | - |
dc.contributor.alternativeName | Lee, Dong Won | - |
dc.contributor.affiliatedAuthor | 이동원 | - |
dc.citation.volume | 53 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 306 | - |
dc.citation.endPage | 317 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE, Vol.53(4) : 306-317, 2023-08 | - |
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