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Tibolone and Breast Cancer

Authors
 Jae Kyung Lee  ;  Hyewon Yun  ;  Heeyon Kim  ;  Bo Hyon Yun  ;  Seok Kyo Seo 
Citation
 Journal of Menopausal Medicine, Vol.29(3) : 92-96, 2023-12 
Journal Title
Journal of Menopausal Medicine
ISSN
 2288-6478 
Issue Date
2023-12
Keywords
Breast density ; Breast neoplasms ; Postmenopausal hormone replacement therapy ; Tibolone
Abstract
Tibolone, a selective tissue estrogenic activity regulator, is a synthetic steroid with distinct pharmacological and clinical characteristics in contrast to conventional menopausal hormone therapy. Tibolone induces estrogenic activity in the brain, vagina, and bone but remains inactive in the endometrium and breast. In particular, several studies have investigated whether tibolone usage increases the risk of breast cancer. This study aims to determine the effects of tibolone on the breast by focusing on the relation between tibolone use and breast cancer. Our investigation emphasizes recent studies, particularly those based on Asian populations.
Files in This Item:
T202400576.pdf Download
DOI
10.6118/jmm.23032
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Seo, Seok Kyo(서석교) ORCID logo https://orcid.org/0000-0003-3404-0484
Yun, Bo Hyon(윤보현) ORCID logo https://orcid.org/0000-0001-5703-797X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/197925
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