0 48

Cited 0 times in

Physical Multimorbidity and Sarcopenia among Adults Aged ≥65 Years in Low- and Middle-Income Countries

 Lee Smith  ;  Jae Il Shin  ;  Guillermo F López Sánchez  ;  Felipe Schuch  ;  Mark Tully  ;  Yvonne Barnett  ;  Laurie Butler  ;  Damiano Pizzol  ;  Nicola Veronese  ;  Pinar Soysal  ;  Karel Kostev  ;  Louis Jacob  ;  Ai Koyanagi 
 GERONTOLOGY, Vol.69(4) : 406-415, 2023-04 
Journal Title
Issue Date
Aged ; Aged, 80 and over ; Chronic Disease ; Cross-Sectional Studies ; Developing Countries ; Female ; Gait ; Hand Strength ; Humans ; Male ; Multimorbidity ; Muscle, Skeletal* ; Pregnancy ; Prevalence ; Sarcopenia* / epidemiology
Epidemiology ; Low- and middle-income countries ; Multi-country ; Multimorbidity ; Older adults ; Sarcopenia
Introduction: Physical multimorbidity is plausibly linked to sarcopenia. However, to date, only a few studies exist on this topic, and none have examined this association in low- and middle-income countries (LMICs). Thus, we aimed to investigate the association between multimorbidity and sarcopenia in a sample of older adults from six LMICs (China, Ghana, India, Mexico, Russia, South Africa). Methods: Cross-sectional, community-based data from the WHO Study on Global Ageing and Adult Health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe sarcopenia was defined as having low SMM, weak handgrip strength, and slow gait speed. A total of 11 physical chronic conditions were assessed and multimorbidity referred to >= 2 chronic conditions. Multivariable logistic regression analysis was conducted. Results: Data on 14,585 adults aged >= 65 years were analysed (mean age 72.6 years, SD 11.5 years; 53.7% females). Adjusted estimates showed that compared to no chronic physical conditions, >= 2 conditions are significantly associated with 1.49 (95% CI = 1.02-2.19) and 2.52 (95% CI = 1.53-4.15) times higher odds for sarcopenia and severe sarcopenia, respectively. Conclusions: In this large sample of older adults from LMICs, physical multimorbidity was significantly associated with sarcopenia and severe sarcopenia. Our study results tentatively suggest that targeting those with multimorbidity may aid in the prevention of sarcopenia, pending future longitudinal research.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.