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이하선에서 발생한 고등급 점액표피양 암종: 증례보고 및 문헌 고찰

Other Titles
 High Grade Mucoepidermoid Carcinoma on Parotid Gland: Case Report and Literature Review 
 정재환  ;  조상흠  ;  홍진호  ;  한승용  ;  김현실  ;  남웅 
 Korean Journal of Oral and Maxillofacial Pathology(대한구강악안면병리학회지), Vol.47(5) : 105-110, 2023-10 
Journal Title
Korean Journal of Oral and Maxillofacial Pathology(대한구강악안면병리학회지)
Issue Date
Mucoepidermoid carcinoma ; Parotid gland tumor ; Grading system ; AFIP system ; Brandwein system
Mucoepidermoid carcinoma (MEC) is the most prevalent malignant tumor originating from the salivary gland. The gradation of MEC is determined histologically based on cellular composition, with high-grade MEC presenting with distinct characteristics and clinical implications. A 56-year-old male presented with a 3-month history of right facial swelling and a recent onset of pain. A subsequent biopsy confirmed a malignant epithelial tumor, with further imaging assisting in determining the surgical approach. Comprehensive surgery, involving the removal of the right submandibular gland and reconstructive procedures, was undertaken. Histopathological evaluation post-surgery confirmed a high-grade MEC. The differentiation between inflammatory conditions and neoplastic lesions in the orofacial region can be challenging. The gradation of MEC is important in guiding therapeutic decisions. Among various classification systems, the Brandwein system offers detailed histopathological criteria that correlate reliably with clinical features. High-grade MECs, although less frequent, are aggressive and have a lower 5-year survival rate. Accurate histopathological diagnosis is crucial in devising an effective treatment plan. The presented case underlines the importance of a meticulous yet periodic follow-up, considering the aggressive nature of high-grade MECs.
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyun Sil(김현실) ORCID logo https://orcid.org/0000-0003-3614-1764
Nam, Woong(남웅) ORCID logo https://orcid.org/0000-0003-0146-3624
Han, Seung-Yong(한승용) ORCID logo https://orcid.org/0000-0002-9558-5384
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