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East Asian Gynecologic Oncology Trial Group (EAGOT): founding history and future perspective

Authors
 Takayuki Enomoto  ;  Aikou Okamoto  ;  Jae-Hoon Kim  ;  Chyong-Huey Lai  ;  Xiaohua Wu  ;  Yong-Man Kim 
Citation
 JOURNAL OF GYNECOLOGIC ONCOLOGY, Vol.34(5) : e86, 2023-09 
Journal Title
JOURNAL OF GYNECOLOGIC ONCOLOGY
ISSN
 2005-0380 
Issue Date
2023-09
MeSH
Asia ; Clinical Trials as Topic* ; Female ; Genital Neoplasms, Female* / therapy ; Humans ; Japan ; Uterine Cervical Neoplasms* / therapy
Keywords
CGCS ; Clinical Trial Group ; EAGOT ; JGOG ; KGOG ; TGOG
Abstract
Racial and regional differences exist in morbidity, histology, drug response, toxicity, and prognosis of gynecologic cancer. However, most large-scale phase III studies have been conducted in Western countries, and these data on Asians, who account for more than half of the world's population, are limited. To build a global clinical trial network in Asia, four clinical trial groups with high expertise and international competitiveness in East Asia, namely the Japanese Gynecologic Oncology Group in Japan, the Korean Gynecologic Oncology Group in Korea, the Taiwanese Gynecologic Oncology Group in Taiwan, and the Chinese Gynecologic Cancer Society in the People's Republic of China, established a new group called the East Asia Gynecologic Oncology Trial Group (EAGOT) on November 19, 2021. It includes four committees: the Cervical Cancer Committee, Uterine Corpus Cancer Committee, Ovarian Cancer Committee, and Translational Research Committee. The purpose of EAGOT is to conduct international clinical trials in an effort to provide the best treatments for Asian women affected by gynecologic cancer. Discussions on new collaborative clinical trials have already begun. The first Annual EAGOT Meeting was held on May 25-27, 2023 in Niigata, Japan. EAGOT, the largest healthcare/investigational innovation network in Asia in the area of gynecologic cancers, will become a platform for establishing standards of care and lead to guidelines for Asian women suffering from gynecologic cancer. The harmonization of regulatory/investigator-initiated clinical trials, simultaneous approval of unapproved drugs in the four countries under a common protocol, and expansion of indications will improve the prognosis of gynecologic cancers in Asia in the near future.
Files in This Item:
T202307196.pdf Download
DOI
10.3802/jgo.2023.34.e86
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Hoon(김재훈) ORCID logo https://orcid.org/0000-0001-6599-7065
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/197453
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