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Efficacy of high-flow nasal oxygen during drug-induced sleep endoscopy in patients with obstructive sleep apnea

Authors
 Sujung Park  ;  So Yeon Kim  ;  Hyun Joo Kim 
Citation
 SLEEP AND BREATHING, Vol.27(5) : 1779-1785, 2023-10 
Journal Title
SLEEP AND BREATHING
ISSN
 1520-9512 
Issue Date
2023-10
MeSH
Endoscopy ; Humans ; Hypoxia ; Oxygen* ; Sleep ; Sleep Apnea, Obstructive*
Keywords
Desaturation ; Drug-induced sleep endoscopy ; High-flow nasal oxygenation ; Hypoxia ; Sleep apnea
Abstract
Purpose: High-flow nasal oxygenation (HFNO) can provide a low level of continuous positive airway pressure and alveolar recruitment. We aimed to compare the efficacy of pre-oxygenation with HFNO and low-flow nasal oxygenation (LFNO) during drug-induced sleep endoscopy (DISE).

Methods: In the LFNO group, preoxygenation was performed for 10 min at 3 L·min-1. In the HFNO group, preoxygenation was performed for 10 min at 30 L·min-1 at a fraction of inspired oxygen of 100% using the Optiflow device. From the start of sedative administration to the end of DISE, vital signs were monitored continuously. The primary outcome was the lowest oxygen saturation (SpO2) during DISE.

Results: Of 24 patients enrolled, 12 were randomly assigned to the LFNO and 12 to the HFNO groups. The prevalence of hypoxia events was 75% in the LFNO group and 58% in the HFNO group. The difference in lowest oxygen saturation between the two groups was not significant between the two groups (P=0.665). The lowest SpO2 during all procedures was comparable between the two groups (86.8 ± 6.5% in the LFNO group and 87.2 ± 8.0% in the HFNO group; P=0.912).

Conclusions: The findings suggest that HFNO may not be superior to LFNO as a preoxygenation tool to prevent hypoxia during DISE.
Full Text
https://link.springer.com/article/10.1007/s11325-023-02785-5
DOI
10.1007/s11325-023-02785-5
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kim, So Yeon(김소연) ORCID logo https://orcid.org/0000-0001-5352-157X
Kim, Hyun Joo(김현주) ORCID logo https://orcid.org/0000-0003-1963-8955
Park, Sujung(박수정) ORCID logo https://orcid.org/0000-0002-2249-3286
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/196579
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