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Association between polycythemia and risk of ischemic stroke in males based on the national health insurance service-health screening cohort
DC Field | Value | Language |
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dc.contributor.author | 강희택 | - |
dc.date.accessioned | 2023-07-12T03:17:04Z | - |
dc.date.available | 2023-07-12T03:17:04Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 1747-4086 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195560 | - |
dc.description.abstract | Background: Polycythemia, a state in which the hematocrit or hemoglobin (Hb) concentration in the peripheral blood increases, is associated with several thrombosis-related diseases, of which cerebral infarction is relatively common. This study aimed to investigate the association between ischemic stroke and polycythemia, as a potential risk factor. Research design and methods: This study included men who had undergone national health checkups between 2002 and 2003; the data were extracted from the Korean National Health Insurance Service-Health Screening database. The primary outcome was the risk ischemic stroke; adjusted hazard ratios (HRs) with 95% confidence intervals (CIs) for ischemic stroke were calculated using Cox proportional hazards regression models. Results: In total, 207,737 male participants aged 40-79 years were included in this study. At the baseline, 13972 (6.7%) participants met the polycythemia criteria (Hb >16.5 g/dL). During the study period, 897 and 12,440 cases of ischemic stroke occurred in the polycythemia and normocythemia (13.0 g/dL ≤ Hb ≤16.5 g/dL) groups, respectively. Compared with the normocythemia group, the polycythemia group showed an adjusted HR (95% CI) for ischemic stroke of 1.12 (1.04-1.20). Conclusions: The risk of ischemic stroke was higher in participants with polycythemia than in those with normocythemia. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Taylor & Francis | - |
dc.relation.isPartOf | EXPERT REVIEW OF HEMATOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Ischemic Stroke* / diagnosis | - |
dc.subject.MESH | Ischemic Stroke* / epidemiology | - |
dc.subject.MESH | Ischemic Stroke* / etiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | National Health Programs | - |
dc.subject.MESH | Polycythemia* / complications | - |
dc.subject.MESH | Polycythemia* / diagnosis | - |
dc.subject.MESH | Polycythemia* / epidemiology | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stroke* / diagnosis | - |
dc.subject.MESH | Stroke* / epidemiology | - |
dc.subject.MESH | Stroke* / etiology | - |
dc.title | Association between polycythemia and risk of ischemic stroke in males based on the national health insurance service-health screening cohort | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Hyo-Sun You | - |
dc.contributor.googleauthor | Sang-Jun Shin | - |
dc.contributor.googleauthor | Joungyoun Kim | - |
dc.contributor.googleauthor | Hee-Taik Kang | - |
dc.identifier.doi | 10.1080/17474086.2023.2218610 | - |
dc.contributor.localId | A00106 | - |
dc.relation.journalcode | J04456 | - |
dc.identifier.eissn | 1747-4094 | - |
dc.identifier.pmid | 37249134 | - |
dc.identifier.url | https://www.tandfonline.com/doi/abs/10.1080/17474086.2023.2218610 | - |
dc.subject.keyword | Cerebrovascular disorders | - |
dc.subject.keyword | Infarction | - |
dc.subject.keyword | Thrombosis | - |
dc.subject.keyword | hemoglobin | - |
dc.subject.keyword | ischemic stroke | - |
dc.subject.keyword | polycythemia | - |
dc.subject.keyword | stroke | - |
dc.contributor.alternativeName | Kang, Hee Taik | - |
dc.contributor.affiliatedAuthor | 강희택 | - |
dc.citation.volume | 16 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 553 | - |
dc.citation.endPage | 559 | - |
dc.identifier.bibliographicCitation | EXPERT REVIEW OF HEMATOLOGY, Vol.16(7) : 553-559, 2023-07 | - |
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