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Inverse Association between Oxidative Balance Score and Incident Type 2 Diabetes Mellitus
DC Field | Value | Language |
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dc.contributor.author | 권유진 | - |
dc.date.accessioned | 2023-07-12T02:52:53Z | - |
dc.date.available | 2023-07-12T02:52:53Z | - |
dc.date.issued | 2023-05 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195428 | - |
dc.description.abstract | Mitigating the risk of type 2 diabetes mellitus (T2DM) can be achieved through the maintenance of a healthy weight, the adoption of a healthy diet, and engaging in regular physical activity. The oxidative balance score (OBS), an integrated measure of pro- and antioxidant exposure conditions, represents an individual's overall oxidative balance status. This study aimed to evaluate the association between OBS and T2DM incidence using data from a large, community-based, prospective cohort study. Data from 7369 participants aged 40-69 years who engaged in the Korean Genome and Epidemiology Study (KoGES) were analyzed. The hazard ratio (HR) and 95% confidence interval (CI) for T2DM incidence of sex-specific OBS tertile groups were calculated using univariable and multivariable Cox proportional hazard regression analyses. During the mean 13.6-year follow-up period, 908 men and 880 women developed T2DM. The fully-adjusted HR (95% CI) for incident T2DM of the middle and highest tertile groups, compared with the referent lowest tertile group, were 0.86 (0.77-1.02) and 0.83 (0.70-0.99) in men and were 0.94 (0.80-1.11) and 0.78 (0.65-0.94) in women, respectively. Individuals with a high OBS are at lower risk for the development of T2DM. This implies that lifestyle modification with more antioxidant properties could be a preventive strategy for T2DM. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI Publishing | - |
dc.relation.isPartOf | NUTRIENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Antioxidants | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / epidemiology | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / etiology | - |
dc.subject.MESH | Diabetes Mellitus, Type 2* / prevention & control | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Oxidative Stress | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Inverse Association between Oxidative Balance Score and Incident Type 2 Diabetes Mellitus | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Yu-Jin Kwon | - |
dc.contributor.googleauthor | Hye-Min Park | - |
dc.contributor.googleauthor | Jun-Hyuk Lee | - |
dc.identifier.doi | 10.3390/nu15112497 | - |
dc.contributor.localId | A04882 | - |
dc.relation.journalcode | J02396 | - |
dc.identifier.eissn | 2072-6643 | - |
dc.identifier.pmid | 37299460 | - |
dc.subject.keyword | Korean genome | - |
dc.subject.keyword | antioxidant | - |
dc.subject.keyword | epidemiology study | - |
dc.subject.keyword | oxidative balance score | - |
dc.subject.keyword | type 2 diabetes mellitus | - |
dc.contributor.alternativeName | Kwon, Yu-Jin | - |
dc.contributor.affiliatedAuthor | 권유진 | - |
dc.citation.volume | 15 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2497 | - |
dc.identifier.bibliographicCitation | NUTRIENTS, Vol.15(11) : 2497, 2023-05 | - |
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