Cited 0 times in
Development and accuracy validation of a fat fraction imaging biomarker for sialadenitis in the parotid gland
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이채나 | - |
dc.contributor.author | 전국진 | - |
dc.contributor.author | 최윤주 | - |
dc.contributor.author | 한상선 | - |
dc.date.accessioned | 2023-07-12T02:51:34Z | - |
dc.date.available | 2023-07-12T02:51:34Z | - |
dc.date.issued | 2023-06 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195421 | - |
dc.description.abstract | Background: The diagnosis of sialadenitis, the most frequent disease of the salivary glands, is challenging when the symptoms are mild. In such cases, biomarkers can be used as definitive diagnostic indicators. Recently, biomarkers have been developed by extracting and analyzing pathological and morphological features from medical imaging. This study aimed to establish a diagnostic reference for sialadenitis based on the quantitative magnetic resonance imaging (MRI) biomarker IDEAL-IQ and assess its accuracy. Methods: Patients with sialadenitis (n = 46) and control subjects (n = 90) that underwent MRI were selected. Considering that the IDEAL-IQ value is a sensitive fat fractional marker to the body mass index (BMI), all subjects were also categorized as under-, normal-, and overweight. The fat fraction of parotid gland in the control and sialadenitis groups were obtained using IDEAL-IQ map. The values from the subjects in the control and sialadenitis groups were compared in each BMI category. For comparison, t-tests and receiver operating characteristic (ROC) curve analyses were performed. Results: The IDEAL-IQ fat faction of the control and sialadenitis glands were 38.57% and 23.69%, respectively, and the differences were significant. The values were significantly lower in the sialadenitis group (P), regardless of the BMI types. The area under the ROC curve (AUC) was 0.83 (cut-off value: 28.72) in patients with sialadenitis. The AUC for under-, normal-, and overweight individuals were 0.78, 0.81, and 0.92, respectively. Conclusions: The fat fraction marker based on the IDEAL-IQ method was useful as an objective indicator for diagnosing sialadenitis. This marker would aid less-experienced clinicians in diagnosing sialadenitis. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BioMed Central | - |
dc.relation.isPartOf | BMC ORAL HEALTH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging / methods | - |
dc.subject.MESH | Overweight | - |
dc.subject.MESH | Parotid Gland* / diagnostic imaging | - |
dc.subject.MESH | Parotid Gland* / pathology | - |
dc.subject.MESH | Salivary Glands | - |
dc.subject.MESH | Sialadenitis* / diagnostic imaging | - |
dc.title | Development and accuracy validation of a fat fraction imaging biomarker for sialadenitis in the parotid gland | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral and Maxillofacial Radiology (영상치의학교실) | - |
dc.contributor.googleauthor | Ari Lee | - |
dc.contributor.googleauthor | Yoon Joo Choi | - |
dc.contributor.googleauthor | Kug Jin Jeon | - |
dc.contributor.googleauthor | Sang-Sun Han | - |
dc.contributor.googleauthor | Chena Lee | - |
dc.identifier.doi | 10.1186/s12903-023-03024-9 | - |
dc.contributor.localId | A05388 | - |
dc.contributor.localId | A03503 | - |
dc.contributor.localId | A05734 | - |
dc.contributor.localId | A04283 | - |
dc.relation.journalcode | J00371 | - |
dc.identifier.eissn | 1472-6831 | - |
dc.identifier.pmid | 37264360 | - |
dc.subject.keyword | Diagnostic imaging | - |
dc.subject.keyword | Imaging biomarker | - |
dc.subject.keyword | Magnetic resonance imaging | - |
dc.subject.keyword | Salivary gland | - |
dc.subject.keyword | Sialadenitis | - |
dc.contributor.alternativeName | Lee, Chena | - |
dc.contributor.affiliatedAuthor | 이채나 | - |
dc.contributor.affiliatedAuthor | 전국진 | - |
dc.contributor.affiliatedAuthor | 최윤주 | - |
dc.contributor.affiliatedAuthor | 한상선 | - |
dc.citation.volume | 23 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 347 | - |
dc.identifier.bibliographicCitation | BMC ORAL HEALTH, Vol.23(1) : 347, 2023-06 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.