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Analgesic effects of combined transversus abdominis plane block and intramuscular electrical stimulation in patients undergoing cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy: a randomized controlled trial
DC Field | Value | Language |
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dc.contributor.author | 김현창 | - |
dc.contributor.author | 박은정 | - |
dc.contributor.author | 박진영 | - |
dc.contributor.author | 백승혁 | - |
dc.contributor.author | 송영 | - |
dc.date.accessioned | 2023-07-12T02:51:06Z | - |
dc.date.available | 2023-07-12T02:51:06Z | - |
dc.date.issued | 2023-05 | - |
dc.identifier.issn | 1743-9191 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195419 | - |
dc.description.abstract | Background: To evaluate the analgesic efficacy of a four-quadrant transversus abdominis plane (4QTAP) block and a combination of 4QTAP block with needle electrical twitch and intramuscular electrical stimulation (NETOIMS) in patients undergoing cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC). Materials and methods: Eighty-one patients who underwent CRS followed by HIPEC were included in this study. Patients were randomly assigned to one of three groups: group 1 (intravenous patient-controlled analgesia, control group), group 2 (preoperative 4QTAP block), and group 3 (preoperative 4QTAP block and postoperative NETOIMS). The primary study endpoint was the pain score assessed by the visual analog scale (VAS: 0, no pain; 10, worst imaginable pain) on postoperative day (POD) 1. Results: The VAS pain score on POD 1 was significantly lower in group 2 than in group 1 (6.0±1.7 and 7.6±1.9, P =0.004), whereas that in group 3 was significantly lower than that in groups 1 and 2 ( P <0.001 and P =0.004, respectively). Opioid consumption and nausea and vomiting incidence during POD 7 were significantly lower in group 3 than in groups 1 and 2. Gait speed and peak cough flow on POD 4 and 7, as well as the quality of recovery (QoR)-40 score on POD 4, were significantly higher in group 3 than in groups 1 and 2. Conclusions: The combination of a 4QTAP block with NETOIMS provided more effective analgesia than a 4QTAP block alone after CRS, followed by HIPEC, and enhanced functional restoration and quality of recovery. Trial registration: ClinicalTrials.gov NCT04981639. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Abdominal Muscles | - |
dc.subject.MESH | Analgesics, Opioid / therapeutic use | - |
dc.subject.MESH | Cytoreduction Surgical Procedures / adverse effects | - |
dc.subject.MESH | Fever | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Nerve Block* / adverse effects | - |
dc.subject.MESH | Pain, Postoperative* / drug therapy | - |
dc.subject.MESH | Pain, Postoperative* / therapy | - |
dc.title | Analgesic effects of combined transversus abdominis plane block and intramuscular electrical stimulation in patients undergoing cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy: a randomized controlled trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Hyun-Chang Kim | - |
dc.contributor.googleauthor | Jinyoung Park | - |
dc.contributor.googleauthor | Jinyoung Oh | - |
dc.contributor.googleauthor | Minjae Kim | - |
dc.contributor.googleauthor | Eun Jung Park | - |
dc.contributor.googleauthor | Seung Hyuk Baik | - |
dc.contributor.googleauthor | Young Song | - |
dc.identifier.doi | 10.1097/JS9.0000000000000383 | - |
dc.contributor.localId | A06091 | - |
dc.contributor.localId | A04572 | - |
dc.contributor.localId | A04941 | - |
dc.contributor.localId | A01827 | - |
dc.contributor.localId | A02036 | - |
dc.relation.journalcode | J01162 | - |
dc.identifier.eissn | 1743-9159 | - |
dc.identifier.pmid | 36999805 | - |
dc.identifier.url | https://journals.lww.com/international-journal-of-surgery/Fulltext/2023/05000/Analgesic_effects_of_combined_transversus.15.aspx | - |
dc.contributor.alternativeName | Kim, Hyun-Chang | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.contributor.affiliatedAuthor | 박은정 | - |
dc.contributor.affiliatedAuthor | 박진영 | - |
dc.contributor.affiliatedAuthor | 백승혁 | - |
dc.contributor.affiliatedAuthor | 송영 | - |
dc.citation.volume | 109 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1199 | - |
dc.citation.endPage | 1207 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF SURGERY, Vol.109(5) : 1199-1207, 2023-05 | - |
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