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Mixed neuroendocrine-non-neuroendocrine carcinoma (MiNEN) in gallbladder with liver metastasis of neuroendocrine carcinoma component: a case report

Authors
 Se In Park  ;  Jae Won Lee  ;  Joo Ho Zhiang  ;  Yeon Seung Chung  ;  Moon Jae Chung  ;  Sung Hyun Kim 
Citation
 JOURNAL OF SURGICAL CASE REPORTS, Vol.2023(3) : rjad132, 2023-03 
Journal Title
 JOURNAL OF SURGICAL CASE REPORTS 
Issue Date
2023-03
Abstract
Mixed neuroendocrine-non-neuroendocrine neoplasms of the gallbladder are rare with a lack of established standardized therapeutic strategies. We report a case of gallbladder mixed neuroendocrine-non-neuroendocrine neoplasm with liver metastasis of neuroendocrine carcinoma. A patient who underwent radical cholecystectomy for gallbladder adenocarcinoma was detected with increasing liver mass, and hepatectomy was performed. Pathological report revealed neuroendocrine carcinoma. To find primary origin, pathological review of the old specimen from previous cholecystectomy with a slightly different perspective was conducted, where the neuroendocrine component was positively dyed. In conclusion, though it might be impossible to review every pathological result in cases with ambiguous findings, reviewing the previous specimen can be a useful option in diagnosis.

Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.
Files in This Item:
T202303174.pdf Download
DOI
10.1093/jscr/rjad132
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Hyun(김성현) ORCID logo https://orcid.org/0000-0001-7683-9687
Chung, Moon Jae(정문재) ORCID logo https://orcid.org/0000-0002-5920-8549
Chung, Yeon Seung(정연승)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/195413
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