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Serodiagnosis of human sparganosis by a monoclonal antibody-based competition ELISA
DC Field | Value | Language |
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dc.contributor.author | 용태순 | - |
dc.date.accessioned | 2023-07-12T00:30:32Z | - |
dc.date.available | 2023-07-12T00:30:32Z | - |
dc.date.issued | 1994-03 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195148 | - |
dc.description.abstract | Competition ELISA test using sparganum specific monoclonal antibodies (Mab) was investigated to improve the diagnostic specificity of sparganosis. By cell fusion, one hybridoma clone secreting anti-sparganum specific Mab was selected (Sp-20), which reacted on bands of 32 kDa and 38 kDa. Sp-20 reacted on calcium corpuscles on IFA. By micro-ELISA, 16 of 17 sparganosis cases (95%) were found positive, but 1 of 18 clonorchiasis cases (5%), 4 of 16 cysticercosis cases (25%) and 2 of 16 normal controls (11%) showed false positive reactions. On the other hand, by competition ELISA using a sparganum specific Mab (Sp-20), 16 out of 17 (95%) of sparganosis cases were found positive, but 2 of 18 clonorchiasis cases (10%), 2 of 16 cysticercosis cases (12%), 3 of 16 paragonimiasis cases (18%) and 1 of 16 normal controls (6%) showed false positive reactions. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Antibodies, Helminth | - |
dc.subject.MESH | Binding, Competitive | - |
dc.subject.MESH | Enzyme-Linked Immunosorbent Assay | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Sparganosis / diagnosis* | - |
dc.subject.MESH | Sparganum / immunology | - |
dc.title | Serodiagnosis of human sparganosis by a monoclonal antibody-based competition ELISA | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Environmental Medical Biology (환경의생물학교실) | - |
dc.contributor.googleauthor | In Sok Yeo | - |
dc.contributor.googleauthor | Tai Soon Yong | - |
dc.contributor.googleauthor | Kyung il Im | - |
dc.identifier.doi | 10.3349/ymj.1994.35.1.43 | - |
dc.contributor.localId | A02424 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 8009896 | - |
dc.contributor.alternativeName | Yong, Tai Soon | - |
dc.contributor.affiliatedAuthor | 용태순 | - |
dc.citation.volume | 35 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 43 | - |
dc.citation.endPage | 48 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.35(1) : 43-48, 1994-03 | - |
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