농약살포자 혈중 콜린에스테라제 활성도의 변화 및 농약성분

Abstract

In order to ascertain the status of health damage among Korean farmers who spray pesticides regularly in summer, blood and urine samples were collected for 88 volunteers during July to September in 1990. Serum cholinesterase activity, parent compounds of pesticides in blood and urine, SGOT SGPT, blood pressure, pulse rate were measured. The results were as follows; 1. Mean cholinesterase activity after spraying pesticides was significantly lower than that before spraying. While proportion of abnormal cholinesterase activity(<1900 U/L) group was 2.3% before spraying pesticides, the proportion of the group after spraying was 22.8% 2. Cholinesterase activity were decreased over 50% in 14.7% of the subjects who can be classified into poisoning group 3. While pulse rate and blood pressure were slightly increased in poisoning group, those were significantly decreased in non-poisoning group. 4. consecutive spraying of pesticide caused further reduction of cholinesterase activity,. 5. Five parent compounds of pesticides frequently used during summer farming were analyzed using 106 blood samples. IBP in one sample and Isoprothiolane in four samples were detected. No parent compounds were detected in urine samples.