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R을 이용한 결과 변수에 따른 최적의 Cut-off Point 결정
DC Field | Value | Language |
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dc.contributor.author | 이혜선 | - |
dc.date.accessioned | 2023-06-14T08:13:30Z | - |
dc.date.available | 2023-06-14T08:13:30Z | - |
dc.date.issued | 2022-12 | - |
dc.identifier.issn | 2950-9394 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/194820 | - |
dc.description.abstract | Clinical research ultimately aimed to promptly diagnose and prevent diseases through precise biomarker development. Finding the optimal cut-off point of a regularly measured biomarker can help its interpretation and ultimately help in disease investigation and diagnosis, more spe cifically in determining the presence of diseases. Therefore, this study aimed to use the charac teristics of outcome variables in clinical research to explain how to determine the optimal cut off point. The outcome variables can be divided into dichotomous, ordinal, and survival types. The optimal cut-off point can be determined by finding points that maximize the Youden in dex, extended Youden index, and log-rank statistics. This study will enable clinical researchers to accurately determine the optimal cut-off points for regularly measured biomarkers, thereby enabling prompt disease diagnosis for effective treatment | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society of Gastrointestinal Cancer Research | - |
dc.relation.isPartOf | Journal of Digestive Cancer Research | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | R을 이용한 결과 변수에 따른 최적의 Cut-off Point 결정 | - |
dc.title.alternative | Determining the Optimal Cut-off Point According to the Outcome Variables Using R | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Yonsei Biomedical Research Center (연세의생명연구원) | - |
dc.contributor.googleauthor | 양주연 | - |
dc.contributor.googleauthor | 이혜선 | - |
dc.identifier.doi | 10.52927/jdcr.2022.10.2.99 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J04452 | - |
dc.identifier.eissn | 2950-9505 | - |
dc.subject.keyword | Optimal cut-off point | - |
dc.subject.keyword | Youden index | - |
dc.subject.keyword | Log-rank statistics | - |
dc.subject.keyword | Biomarkers | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.affiliatedAuthor | 이혜선 | - |
dc.citation.volume | 10 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 99 | - |
dc.citation.endPage | 106 | - |
dc.identifier.bibliographicCitation | Journal of Digestive Cancer Research, Vol.10(2) : 99-106, 2022-12 | - |
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