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Evaluation and analysis of radiation exposure to normal tissues during gamma knife radiosurgery for vestibular schwannoma

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dc.date.accessioned2023-06-02T00:53:30Z-
dc.date.available2023-06-02T00:53:30Z-
dc.date.issued2022-07-
dc.identifier.issn2322-3243-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/194496-
dc.description.abstractBackground: A follow-up study of gamma knife radiosurgery has shown that postoperative radiation necrosis, radiation-induced edema, and malignant metastasis may occur. This may be due to secondary radiation exposure, therefore, it becomes necessary to actively reduce exposure to normal organs. Materials and Methods: In this study, the secondary radiation dose to the surrounding normal organs was measured during gamma-knife radiosurgery for vestibular schwannoma disease. Using a human pediatric phantom and a glass dosimeter, a treatment plan was established according to the tumor volume, and then the exposure dose to important normal organs in both eyes, thyroid gland, sternum, and both lungs was measured. Results: According to this study, the cancer occurrence probability due to secondary exposure was calculated to be 7 cases per 100,000 people up to the case of the eye and thyroid gland. Exposure doses of 100.2±0.79 mGy or more were measured in both eyes, which is approximately 1000 times that of a chest X-ray or a flight from Seoul to New York. This indicates exposure through gamma knife surgery. The dose to the thyroid gland was 12.7±0.05 mGy, which exceeds the effective dose of 10 mSv in abdominal computed tomography. Conclusion: By measuring the secondary exposure dose to normal organs during gamma-knife surgery for vestibular schwannoma disease, it was confirmed that the eyes and thyroid gland were exposed dangerously. Therefore, for pediatric patients specifically, a treatment plan that actively reduces secondary exposure is required.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBaresh-e-Danesh Press-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF RADIATION RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleEvaluation and analysis of radiation exposure to normal tissues during gamma knife radiosurgery for vestibular schwannoma-
dc.typeArticle-
dc.contributor.collegeOthers-
dc.contributor.departmentSeverance Hospital (세브란스병원)-
dc.contributor.googleauthorJ.A. Lee-
dc.contributor.googleauthorS.R. Kim-
dc.contributor.googleauthorS.H. Yoon-
dc.contributor.googleauthorJ.S. Kim-
dc.contributor.googleauthorH.J. Yang-
dc.contributor.googleauthorG.H. Kim-
dc.identifier.doi10.52547/ijrr.20.3.8-
dc.relation.journalcodeJ03457-
dc.identifier.eissn2345-4229-
dc.subject.keywordGamma knife radiosurgery-
dc.subject.keywordsecondary radiation exposure-
dc.subject.keywordsecondary cancer-
dc.subject.keywordVestibular schwannoma-
dc.citation.volume20-
dc.citation.number3-
dc.citation.startPage571-
dc.citation.endPage578-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF RADIATION RESEARCH, Vol.20(3) : 571-578, 2022-07-
Appears in Collections:
6. Others (기타) > Severance Hospital (세브란스병원) > 1. Journal Papers

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