0 208

Cited 0 times in

Reduced grip strength potentially indicates depression: Investigating multicontinental databases

Authors
 Jae Won Oh  ;  Sun Mi Kim  ;  Deokjong Lee  ;  Dong Keon Yon  ;  Seung Won Lee  ;  Lee Smith  ;  Karel Kostev  ;  Ai Koyanagi  ;  Marco Solmi  ;  Andre F Carvalho  ;  Jae Il Shin  ;  Nak-Hoon Son  ;  San Lee 
Citation
 JOURNAL OF AFFECTIVE DISORDERS, Vol.323 : 426-434, 2023-02 
Journal Title
JOURNAL OF AFFECTIVE DISORDERS
ISSN
 0165-0327 
Issue Date
2023-02
MeSH
Adult ; Brazil ; China ; Cross-Sectional Studies ; Depression* / complications ; Depression* / epidemiology ; Female ; Hand Strength* ; Humans ; Male ; Middle Aged
Keywords
Depression ; Global databases ; Handgrip strength ; Middle-aged ; Older adults
Abstract
Background: Multi-national studies in the association between handgrip strength and depression in middle and older aged adults are limited. Hence, Brazil, China, Europe, Korea, United Kingdom (UK) and United States (US) datasets were utilized to investigate this association.

Methods: A cross-sectional study was conducted with 51,285 participants aged >45 years. Handgrip strength scores were divided into quartiles, groups 1 (highest) to 4 (lowest) in each database, and depression measures converted to binary scores.

Results: Males in China and UK reported higher adjusted odds ratios (aORs) of depression for groups 2, 3, and 4 than for group 1. Brazil, US, and Korea reported greater aORs in groups 3 and 4 whereas Europe demonstrated increased aORs for group 4 only. Among females, China, Brazil, US, and Korea showed high aORs across all groups, while UK and Europe reported increased aORs for group 4 only. Highest ORs were reported from Korea in group 4 for males (aOR: 3·09; 95 % CI: 2·15-4·43; p < 0·001) and females (aOR: 3·74; 95 % CI: 2·78-5·03; p < 0·001). When removing the regional factor, aORs were higher in lower groups, with the highest reported from group 4 for males (aOR: 2·32; 95 % CI: 2·09-2·58; p < 0·001) and females (aOR: 2·11; 95 % CI: 1·95-2·29; p < 0·001).

Limitations: Being a cross-sectional study, the results were not able to establish the causal direction between handgrip strength and depression.

Conclusion: Lower handgrip strength was associated with an increased likelihood of depression. Early assessment of handgrip strength may identify populations at-risk for depression among middle and older aged adults.
Full Text
https://www.sciencedirect.com/science/article/pii/S0165032722013660
DOI
10.1016/j.jad.2022.12.006
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
Lee, Deokjong(이덕종) ORCID logo https://orcid.org/0000-0002-5425-4677
Lee, San(이산) ORCID logo https://orcid.org/0000-0003-4834-8463
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/193744
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links