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Recent fall and high imminent risk of fracture in older men and women

Authors
 Kyoung Min Kim  ;  Li-Yung Lui  ;  Steven R Cummings 
Citation
 AGE AND AGEING, Vol.51(6) : afac141, 2022-06 
Journal Title
AGE AND AGEING
ISSN
 0002-0729 
Issue Date
2022-06
MeSH
Aged ; Bone Density ; Female ; Hip Fractures* / diagnosis ; Hip Fractures* / epidemiology ; Hip Fractures* / etiology ; Humans ; Male ; Osteoporotic Fractures* / epidemiology ; Osteoporotic Fractures* / etiology ; Osteoporotic Fractures* / prevention & control ; Prospective Studies ; Risk Factors
Keywords
fall ; fracture ; older people ; osteoporosis
Abstract
Background: despite fall history being a well-known risk factor for falls and fractures, the association between very recent falls and imminent fracture risk is not clearly elucidated.

Objective: to study the very recent (<4 months) fall-related absolute risk of fractures in the following year.

Methods: two large prospective cohort studies of women (Study of Osteoporotic Fractures [SOF]) and men (Osteoporotic Fractures in Men Study [MrOS]) aged 65 years or older were included. Data on falls were collected every 4 months, and the primary outcomes were any non-spine and hip fractures in the next 12 months.

Results: a total of 9,704 women contributed 419,149, and 5,994 men contributed 223,885 four-monthly periods of observations during the 14.8-year SOF and 12.6-year MrOS follow-up. Falls within 4 months indicated a high risk of non-spine and hip fractures in the following year for both sexes; in women, a recent fall indicated an 8.1% absolute risk of a non-spine fracture within 1 year, a 2.5-fold higher risk than that in women without falls, a 2.5% absolute risk of hip fracture, and a 3.1-fold increased risk. Falls increased the risk of fractures regardless of whether a fracture occurred or not. Men had similar risk patterns, albeit with a lower absolute risk of fracture.

Conclusions: in older people, a fall within 4 months indicates a high risk of fracture in the next year, regardless of fracture occurrence. A recent fall warrants urgent evaluation and consideration of treatments to reduce the imminent risk of fractures.
Full Text
https://academic.oup.com/ageing/article/51/6/afac141/6618058
DOI
10.1093/ageing/afac141
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Min(김경민)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/193178
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