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Disordered plasmonic substrate-based wide-field super-resolution imaging
DC Field | Value | Language |
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dc.contributor.author | 신전수 | - |
dc.contributor.author | 이우중 | - |
dc.date.accessioned | 2023-03-10T01:07:04Z | - |
dc.date.available | 2023-03-10T01:07:04Z | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 1605-7422 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/193030 | - |
dc.description.abstract | We have investigated the feasibility of disordered plasmonic nanocomposites for super-resolution imaging. Annealing-based nanocomposite substrate has a great potential in biomedical optical and sensing technology because it can be mass-produced without difficult manufacturing processes. We introduce a new approach for wide-field super-resolution fluorescence imaging based on the nanocomposite island substrates, which we call nanospeckle illumination microscopy (NanoSIM). Near-field speckle patterns produced on disordered nanoisland substrates can help reconstruction of high-resolution fluorescence images with appropriate basis images. We have acquired basis images using azimuthal scanning illumination (ASI). Each ASI produces nonuniform nanoscale near-field speckles which can excite fluorescent dyes within a subdiffraction-limited area. While exploiting the random nature of plasmonic nanocomposite, NanoSIM does not require any specific polarization state to be maintained for ASI. We have tested NanoSIM to obtain super-resolved mages of molecules on the HeLa cell membrane. The full-width-at-half maximum was shown to improve by more than three times over the diffraction-limit with 360 basis images. Reconstructed images of gangliosides distribution on the HeLa cell suggest that fewer basis images may produce almost the same resolution with a shorter computation time. The optical resolution and sensitivity of disordered plasmonic substrate can be further enhanced by controlling the geometrical features of nanoislands structure. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | SPIE | - |
dc.relation.isPartOf | Progress in Biomedical Optics and Imaging - Proceedings of SPIE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Disordered plasmonic substrate-based wide-field super-resolution imaging | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Microbiology (미생물학교실) | - |
dc.contributor.googleauthor | Hongki Lee | - |
dc.contributor.googleauthor | Hajun Yoo | - |
dc.contributor.googleauthor | Woo Joong Rhee | - |
dc.contributor.googleauthor | Gwiyeong Moon | - |
dc.contributor.googleauthor | Changhun Lee | - |
dc.contributor.googleauthor | Jeon-Soo Shin | - |
dc.contributor.googleauthor | Donghyun Kim | - |
dc.identifier.doi | 10.1117/12.2609401 | - |
dc.contributor.localId | A02144 | - |
dc.relation.journalcode | J02551 | - |
dc.identifier.url | https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11978/119780A/Disordered-plasmonic-substrate-based-wide-field-super-resolution-imaging/10.1117/12.2609401.short | - |
dc.contributor.alternativeName | Shin, Jeon Soo | - |
dc.contributor.affiliatedAuthor | 신전수 | - |
dc.citation.volume | 11978 | - |
dc.citation.startPage | 119780A | - |
dc.identifier.bibliographicCitation | Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.11978 : 119780A, 2022-02 | - |
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