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Dosimetric calibration of nanodot optically stimulated luminescent dosimeter for intraoperative radiotherapy with low-energy X-rays

Authors
 Yeonho Choi  ;  Jiwon Sung  ;  Kwangwoo Park  ;  Ho Lee 
Citation
 JOURNAL OF THE KOREAN PHYSICAL SOCIETY, Vol.81 : 1100-1106, 2022-08 
Journal Title
JOURNAL OF THE KOREAN PHYSICAL SOCIETY
ISSN
 0374-4884 
Issue Date
2022-08
Keywords
Intraoperative radiotherapy ; In vivo dosimetry ; Optically stimulated luminescent dosimeter ; Low energy ; Dosimetric characteristic
Abstract
The purpose of this study was to evaluate the dosimetric characteristics of optically stimulated luminescent dosimeters (OSLDs) for application in intraoperative radiotherapy (IORT). Dose measurements were performed using a customized phantom fabricated using a three-dimensional (3D) printer and a low-energy (50 kV) X-ray INTRABEAM™ system (Carl Zeiss Surgical GmbH, Oberkochen, Germany). The phantom was equipped with a housing slot for the placement of parallel plate ionization chamber or OSLD. Dosimetric characteristics of the OSLD, i.e. radiation sensitivity, linearity, and reproducibility, were analyzed. In addition, the variation in sensitivity after the irradiation with high dose was estimated. After the irradiation of 1 Gy to the 80 OSLDs, measured doses were to range between 0.92 Gy and 1.04 Gy, with an average sensitivity of 2.1%. To ensure the reproducibility of the OSLDs, the sensitivity was reduced via repeated measurements—a decrease in sensitivity of approximately 6% is observed. After the irradiation with high dose, evaluation of reproducibility revealed variations in sensitivity, with an average sensitivity of 2.9%. Therefore, the dosimetric corrections are necessary for the OSLD based on measurements in IORT environments. The use of the aforementioned correction factors is expected to improve the precision of in vivo dosimetry during IORT.
Full Text
https://link.springer.com/article/10.1007/s40042-022-00570-3
DOI
10.1007/s40042-022-00570-3
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Park, Kwang Woo(박광우) ORCID logo https://orcid.org/0000-0002-9843-7985
Sung, Jiwon(성지원)
Lee, Ho(이호) ORCID logo https://orcid.org/0000-0001-5773-6893
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/192733
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