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Prophylactic antibiotics may not be necessary for transoral endoscopic thyroidectomy

 Jun Sung Lee  ;  Hee Jun Kim  ;  Jin Seok Lee  ;  Hyeok Jun Yun  ;  Suji Lee  ;  Jae-Ho Cheong  ;  Soo Young Kim  ;  Seok-Mo Kim  ;  Hojin Chang  ;  Yong Sang Lee  ;  Cheong Soo Park  ;  Hang-Seok Chang 
 FRONTIERS IN SURGERY, Vol.9 : 940391, 2022-08 
Journal Title
Issue Date
antibiotics ; culture ; surgical site infection ; thyroid cancer ; transoral thyroidectomy
Background: With the recent advances in thyroid cancer surgery techniques and the increasing number of patients concerned about cosmetics, the use of transoral endoscopic thyroidectomy is increasing globally. The aim of this study was to determine whether transoral endoscopic thyroidectomy is truly a clean-contaminated surgery.

Methods: From September 2016 to April 2018, 20 patients with thyroid cancer underwent transoral endoscopic thyroidectomy performed by a single surgeon at Gangnam Severance Hospital. Before and after surgery, the oral cavity was swabbed to obtain culture samples, and antibiotics were administered before and after surgery each once.

Results: Of the total 20 patients, no bacteria were identified before or after surgery in eight (40%) patients. Bacteria were identified both before and after surgery in seven patients (35%). In four patients (20%), bacteria were not identified before surgery, but bacteria were identified after surgery. Bacteria were identified before surgery but not after surgery in one patient (5%). No surgical site infection was observed. All the bacteria identified were normal flora of the oral cavity and skin.

Conclusions: There was no difference between the preoperative culture and postoperative culture of the oral cavity in patients undergoing TOET, and there were no postoperative surgical site infection with prophylactic pre & post-operative antibiotics use. Considering the patient's position and surgical extent in TOET, it appears to be difficult for non-indigenous bacteria to invade the surgical site in oral cavity.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seok Mo(김석모) ORCID logo https://orcid.org/0000-0001-8070-0573
Yun, Hyeok Jun(윤혁준) ORCID logo https://orcid.org/0000-0001-6004-0782
Lee, Yong Sang(이용상) ORCID logo https://orcid.org/0000-0002-8234-8718
Lee, Jun Sung(이준성)
Lee, Jin-Seok(이진석)
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
Chang, Ho Jin(장호진) ORCID logo https://orcid.org/0000-0002-8940-3484
Cheong, Jae Ho(정재호) ORCID logo https://orcid.org/0000-0002-1703-1781
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