Review—Lab-in-a-Mouth and Advanced Point-of-Care Sensing Systems: Detecting Bioinformation from the Oral Cavity and Saliva
Authors
Chochanon Moonla ; Don Hui Lee ; Dinesh Rokaya ; Natcha Rasitanon ; Goma Kathayat ; Won-Yong Lee ; Jayoung Kim ; Itthipon Jeerapan
Citation
ECS Sensors Plus, Vol.1(2) : 021603, 2022-06
Journal Title
ECS Sensors Plus
Issue Date
2022-06
Abstract
Cavitas sensors and point-of-need sensors capable of providing physical and biochemical information from the oral cavity and saliva have attracted great attention because they offer remarkable advantages for noninvasive sensing systems. Herein, we introduce the basic anatomy and physiology of important body cavities to understand their characteristics as it is a pivotal foundation for the successful development of in-mouth devices. Next, the advanced development in lab-in-a-mouth sensors and point-of-need sensors for analyzing saliva are explained. In addition, we discuss the integrations of artificial intelligence and electronic technologies in smart sensing networks for healthcare systems. This review ends with a discussion of the challenges, future research trends, and opportunities in relevant disciplines. Mouthguard-based sensors and conventional salivary sensing devices will continue to be significant for the progress in the next-generation sensing technologies and smart healthcare systems.