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Short-term outcomes of stents in obstructive rectal cancer: A systematic review and meta-analysis

Authors
 Nora H Trabulsi  ;  Hajar M Halawani  ;  Esraa A Alshahrani  ;  Rawan M Alamoudi  ;  Sama K Jambi  ;  Nouf Y Akeel  ;  Ali H Farsi  ;  Mohammed O Nassif  ;  Ali A Samkari  ;  Abdulaziz M Saleem  ;  Nadim H Malibary  ;  Mohammad M Abbas  ;  Luca Gianotti  ;  Antonietta Lamazza  ;  Jin Young Yoon  ;  Nada J Farsi 
Citation
 SAUDI JOURNAL OF GASTROENTEROLOGY, Vol.27(3) : 127-135, 2021-05 
Journal Title
SAUDI JOURNAL OF GASTROENTEROLOGY
ISSN
 1319-3767 
Issue Date
2021-05
MeSH
Humans ; Rectal Neoplasms* / surgery ; Self Expandable Metallic Stents* ; Stents ; Treatment Outcome
Keywords
Complication ; obstruction ; rectal cancer ; stent
Abstract
Background: With acute obstruction due to rectal or recto-sigmoid cancer, the safety and success of deploying self-expandable metal stents has been controversial. The aim of this systematic review was to synthesize the existing evidence on the outcomes and complication rates of stent placement in these patients.

Methods: We performed a literature search of PubMed by using appropriate keywords, and manual reference screening of included articles was done. The article screening, data extraction, and quality assessment was done by four independent reviewers. A meta analyses was performed for the main outcome measures: technical and clinical success and complication rates.

Results: We identified 962 articles in the search. After applying inclusion and exclusion criteria, we included 32 articles in the meta-analysis. The pooled technical success rate across 26 studies that reported it was 97% [95% confidence interval (CI): 95%-99%] without evidence of significant heterogeneity (I2 = 0.0%, P = 0.84), and the clinical success rate across 26 studies that reported it was 69% (95% CI: 58%-79%) with evidence of significant heterogeneity (I2 = 81.7%, P < 0.001). The pooled overall complication rate across the 32 studies was 28% (95% CI: 20%-37%) with evidence of significant heterogeneity (I2 = 79.3%, P < 0.001).

Conclusion: The use of rectal stents in obstructing rectal or recto-sigmoid tumors seems to be technically feasible. A high rate of technical success, however, does not always translate into clinical success. A considerable complication rate is associated with this approach. Randomized controlled trials are needed to compare the outcomes of rectal stent placement with those of surgery.
DOI
10.4103/sjg.sjg_506_20
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/190945
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