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Development of a hybrid magnetic resonance/computed tomography-compatible phantom for magnetic resonance guided radiotherapy

Authors
 Min-Joo Kim  ;  Seu-Ran Lee  ;  Kyu-Ho Song  ;  Hyeon-Man Baek  ;  Bo-Young Choe  ;  Tae Suk Suh 
Citation
 JOURNAL OF RADIATION RESEARCH, Vol.61(2) : 314-324, 2020-03 
Journal Title
JOURNAL OF RADIATION RESEARCH
ISSN
 0449-3060 
Issue Date
2020-03
MeSH
Humans ; Magnetic Resonance Imaging* ; Phantoms, Imaging* ; Radiotherapy Dosage ; Radiotherapy, Image-Guided* ; Signal Processing, Computer-Assisted ; Tomography, X-Ray Computed*
Keywords
magnetic resonance image ; computed tomography ; magnetic resonance guided radiotherapy ; tissue equivalent ; radiation dose calculation
Abstract
The purpose of the present study was to develop a hybrid magnetic resonance/computed tomography (MR/CT)-compatible phantom and tissue-equivalent materials for each MR and CT image. Therefore, the essential requirements necessary for the development of a hybrid MR/CT-compatible phantom were determined and the development process is described. A total of 12 different tissue-equivalent materials for each MR and CT image were developed from chemical components. The uniformity of each sample was calculated. The developed phantom was designed to use 14 plugs that contained various tissue-equivalent materials. Measurement using the developed phantom was performed using a 3.0-T scanner with 32 channels and a Somatom Sensation 64. The maximum percentage difference of the signal intensity (SI) value on MR images after adding K-2 CO3 was 3.31%. Additionally, the uniformity of each tissue was evaluated by calculating the percent image uniformity (%PIU) of the MR image, which was 82.18 +/- 1.87% with 83% acceptance, and the average circular-shaped regions of interest (ROIs) on CT images for all samples were within +/- 5 Hounsfield units (HU). Also, dosimetric evaluation was performed. The percentage differences of each tissue-equivalent sample for average dose ranged from -0.76 to 0.21%. A hybrid MR/CT-compatible phantom for MR and CT was investigated as the first trial in this field of radiation oncology and medical physics.
Files in This Item:
T9992020424.pdf Download
DOI
10.1093/jrr/rrz094
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/190199
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