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The predicting value of resting heart rate to identify undiagnosed diabetes in Korean adult: Korea National Health and Nutrition Examination Survey

 Dong-Hyuk Park  ;  Wonhee Cho  ;  Yong-Ho Lee  ;  Sun Ha Jee  ;  Justin Y Jeon 
 EPIDEMIOLOGY AND HEALTH, Vol.44 : e2022009, 2022-05 
Journal Title
Issue Date
Korea National Health and Nuturition Examination ; Resting heart rate ; Risk score model ; Undiagnosed diabetes
Objectives: The purpose of the current study is to examine 1) whether the addition of resting heart rate (RHR) to existing undiagnosed diabetes (UnDM) prediction model would improve predictability, 2) to develop and validate UnDM prediction model by only using easily assessable variables such as age, gender, RHR and waist circumference (WC).

Methods: Korea National Health and Nutrition Examination Survey (KNHANES) 2010, 2012, 2014, 2016 data were used to develop the model (model building set, N=19,675) and KNHANES data from 2011, 2013, 2015, 2017 were used to validate the model (validation set, N=19,917). UnDM was defined as a fasting glucose level ≥ 126mg/dL or hemoglobin A1c ≥6.5%, yet has not been diagnosed by doctors. SPSS logistic regression analysis was used to determine predictors of UnDM.

Results: Age, RHR, waist circumference (WC) were associated with UnDM. When RHR was added to the existing model, sensitivity was reduced (86% vs. 73%) while specificity was increased (49% vs. 65%), expressed as higher Youden index (35 vs. 38). When only age, sex, WC and RHR were used in the model, sensitivity of 70%, and specificity of 67% with Youden index of 37 were observed.

Conclusion: Adding RHR to existing UnDM prediction model improved specificity and Youden index. Furthermore, prediction model only used age, sex, RHR and WC were not inferior to existing prediction model.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Lee, Yong Ho(이용호) ORCID logo https://orcid.org/0000-0002-6219-4942
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
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