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How Long to Continue Eyelid Hygiene to Treat Meibomian Gland Dysfunction

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dc.contributor.author김태임-
dc.contributor.author서경률-
dc.contributor.author안현민-
dc.contributor.author이형근-
dc.contributor.author전익현-
dc.contributor.author지용우-
dc.date.accessioned2022-03-11T06:11:46Z-
dc.date.available2022-03-11T06:11:46Z-
dc.date.issued2022-02-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/187981-
dc.description.abstractTo determine the efficacy duration of eyelid hygiene for meibomian gland dysfunction (MGD) treatment, a total of 1015 participants with primary MGD, followed for at least 6 months, were enrolled. The participants were classified into the eyelid hygiene group and the control group. The participants who had stopped eyelid hygiene at any point in the observation period after the initial 2 months were classified into the withdrawal group. Analysis was conducted with a generalized linear mixed model. Treatment group, age, sex, ocular surface inflammation, anti-inflammatory treatments, and baseline MGD subtype were considered as fixed effects, and the individual factor was considered as a random effect. The MGD stage decreased significantly for the observational period in the eyelid hygiene group (p < 0.001). Approximately 40.1% of the participants continuously maintained eyelid hygiene throughout the observational period. The MGD stage in the eyelid hygiene group continued to decrease for 6 months and was maintained thereafter. After 4 months of stopping eyelid hygiene, the MGD stage in the withdrawal group was worse than in the eyelid hygiene group (p < 0.001) and similar to that in the control group (p = 0.762). Maintaining eyelid hygiene was significantly effective in MGD treatment. Efficacy increased with treatment for 6 months, and the efficacy duration was maintained for 4 months even after stopping eyelid hygiene. Therefore, we recommend that patients with MGD maintain eyelid hygiene, and compliance should be checked continuously.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleHow Long to Continue Eyelid Hygiene to Treat Meibomian Gland Dysfunction-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학교실)-
dc.contributor.googleauthorHyunmin Ahn-
dc.contributor.googleauthorBo Yi Kim-
dc.contributor.googleauthorJinyoung Kim-
dc.contributor.googleauthorYong Woo Ji-
dc.contributor.googleauthorIkhyun Jun-
dc.contributor.googleauthorTae-Im Kim-
dc.contributor.googleauthorHyung Keun Lee-
dc.contributor.googleauthorKyoung Yul Seo-
dc.identifier.doi10.3390/jcm11030529-
dc.contributor.localIdA01080-
dc.contributor.localIdA01870-
dc.contributor.localIdA06230-
dc.contributor.localIdA03303-
dc.contributor.localIdA03541-
dc.contributor.localIdA03967-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.identifier.pmid35159982-
dc.subject.keywordcompliance-
dc.subject.keywordeyelid hygiene-
dc.subject.keywordmeibomian gland dysfunction-
dc.contributor.alternativeNameKim, Tae Im-
dc.contributor.affiliatedAuthor김태임-
dc.contributor.affiliatedAuthor서경률-
dc.contributor.affiliatedAuthor안현민-
dc.contributor.affiliatedAuthor이형근-
dc.contributor.affiliatedAuthor전익현-
dc.contributor.affiliatedAuthor지용우-
dc.citation.volume11-
dc.citation.number3-
dc.citation.startPage529-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.11(3) : 529, 2022-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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